Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 10/20 | 0.51 |
| ▸ | MAOA | P21397 | 6/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21034783 | 0.86 | ALDH1A1 (0.53) | ALDH1A1HPGDCYP3A4MAPK1MAOB | |
| SCHEMBL8116180 | 0.85 | PPARA (0.57) | ALDH1A1HPGDCYP3A4MAPK1MAOB | |
| SCHEMBL925372 | 0.84 | TRPA1 (0.57) | TRPA1ALDH1A1MAOBMAOAHSD17B1 | |
| SCHEMBL11938337 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HPGDCYP3A4MAPK1MAOB | |
| SCHEMBL2126940 | 0.84 | PPARA (0.65) | TRPA1ALDH1A1HPGDCYP3A4PPARA | |
| SCHEMBL21900873 | 0.83 | HSD17B1 (0.46) | TRPA1ALDH1A1CYP3A4MAPK1MAOB | |
| SCHEMBL14072398 | 0.82 | TRPA1 (0.55) | TRPA1ALDH1A1HPGDMAPK1PPARA | |
| SCHEMBL27919396 | 0.82 | HSP90AB1 (0.67) | TRPA1ALDH1A1HPGDCYP3A4MAPK1 | |
| SCHEMBL29827550 | 0.82 | HSD17B1 (0.58) | TRPA1ALDH1A1HPGDMAOBMAOA | |
| SCHEMBL3737547 | 0.82 | HSD17B1 (0.58) | TRPA1ALDH1A1HPGDMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511233-B | Thiazolo [2,3-b ] oxazolone compound and preparation method and application thereof | 成都大学 | 2022-01-25 | — | — | CN | disclosed |
| US-20150306002-A1 | 3-HYDROXY-4-OXO-4H-PYRAN- OR 3-HYDROXY-4-OXO-1,4-DIHYDROPYRIDINE DERIVATIVES AS PROTEIN-ADHESIVE ACTIVE SUBSTANCES | MERCK PATENT GMBH (DE) | 2015-10-29 | — | — | US | disclosed |
| WO-2010105851-A1 | PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-23 | — | — | WO | disclosed |
| US-20100151508-A1 | COMPOUNDS | THE ROBERT GORDON UNIVERSITY | 2010-06-17 | — | — | US | disclosed |
| US-20100151508-A1 | COMPOUNDS | THE ROBERT GORDON UNIVERSITY | 2010-06-17 | — | — | US | disclosed |
| US-20100151508-A1 | COMPOUNDS | THE ROBERT GORDON UNIVERSITY | 2010-06-17 | — | — | US | disclosed |
| US-7601754-B2 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2009-10-13 | — | — | US | disclosed |
| US-7601754-B2 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2009-10-13 | — | — | US | disclosed |
| US-7601754-B2 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2009-10-13 | — | — | US | disclosed |
| WO-2008062184-A1 | COMPOUNDS | THE ROBERT GORDON UNIVERSITY (GB) | 2008-05-29 | — | — | WO | disclosed |
| EP-1534698-B1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | ROWETT RES INST (GB) | 2007-09-19 | — | — | EP | disclosed |
| EP-1534698-B1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | ROWETT RES INST (GB) | 2007-09-19 | — | — | EP | disclosed |
| US-20060137207-A1 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2006-06-29 | — | — | US | disclosed |
| EP-1534698-A1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | The Rowett Research Institute (GB) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004007475-A1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | ROWETT RESEARCH INSTITUTE (GB) | 2004-01-22 | — | — | WO | disclosed |
| EP-0634409-B1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0634409-A1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993022311-A1 | FUNGICIDAL 1,3,4-OXADIAZINES AND 1,3,4-THIADIAZINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150306002-A1 | 3-HYDROXY-4-OXO-4H-PYRAN- OR 3-HYDROXY-4-OXO-1,4-DIHYDROPYRIDINE DERIVATIVES AS PROTEIN-ADHESIVE ACTIVE SUBSTANCES | S100A4, CUTA, OCIAD1 | TRPA1 615/4885ALDH1A1 169/4885HPGD 361/4885 |
| US-20100151508-A1 | COMPOUNDS | NFE2L2, RBBP4, GPX4 | TRPA1 2270/4885ALDH1A1 1424/4885HPGD 1071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.