Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.38 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.37 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12651386 | 0.95 | FAAH (0.45) | FAAHOPRM1OPRD1OPRK1BMPR1B | |
| Trifluoroacetic Acid SCHEMBL3340014 | 0.88 | CTSC (0.44) | FAAHOPRM1OPRD1OPRK1BMPR1B | |
| Trifluoroacetic Acid SCHEMBL3341377 | 0.86 | OPRM1 (0.45) | FAAHOPRM1OPRD1OPRK1AKR1C3 | |
| Trifluoroacetic Acid SCHEMBL3337465 | 0.86 | DPP4 (0.42) | FAAHOPRM1OPRD1OPRK1DPP4 | |
| Trifluoroacetic Acid SCHEMBL3339667 | 0.86 | DPP4 (0.42) | FAAHOPRM1OPRD1OPRK1AKR1C3 | |
| Trifluoroacetic Acid SCHEMBL3339670 | 0.85 | BMPR1B (0.37) | OPRM1OPRD1OPRK1BMPR1BBMPR1A | |
| Trifluoroacetic Acid SCHEMBL3346142 | 0.85 | OPRM1 (0.45) | FAAHOPRM1OPRD1OPRK1AKR1C3 | |
| Trifluoroacetic Acid SCHEMBL3340800 | 0.84 | AKR1C3 (0.48) | FAAHOPRM1OPRD1OPRK1AKR1C3 | |
| Trifluoroacetic Acid SCHEMBL3346083 | 0.84 | OPRM1 (0.44) | FAAHOPRM1OPRD1OPRK1AKR1C3 | |
| Trifluoroacetic Acid SCHEMBL3340025 | 0.84 | OPRM1 (0.47) | FAAHOPRM1OPRD1OPRK1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140323487-A1 | Novel Compounds As Antagonists Or Inverse Agonists At Opioid Receptors | GLAXOSMITHKLINE LLC | 2014-10-30 | — | — | US | disclosed |
| US-20100113512-A1 | METHOD OF TREATMENT USING NOVEL ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | IGNAR DIANE MICHELE | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113512-A1 | METHOD OF TREATMENT USING NOVEL ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | OPRL1, OPRD1, OPRK1 | FAAH 166/4885OPRM1 4/4885OPRD1 2/4885 |
| US-20140323487-A1 | Novel Compounds As Antagonists Or Inverse Agonists At Opioid Receptors | OPRL1, OPRM1, OPRK1 | FAAH 397/4885OPRM1 2/4885OPRD1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.