Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.41 |
| ▸ | DAO | P14920 | 3/20 | 0.38 |
| ▸ | DDO | Q99489 | 2/20 | 0.38 |
| ▸ | TYMS | P04818 | 3/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351515 | 0.82 | ALDH1A1 (0.44) | PDE10APTGIRPTGDRPTGDR2HDAC1 | |
| SCHEMBL3350433 | 0.79 | ALDH1A1 (0.43) | DAODDOALKBH3KDM4EALDH1A1 | |
| SCHEMBL3344021 | 0.78 | AKR1B1 (0.39) | DAODDOPTGDR2 | |
| SCHEMBL3349053 | 0.70 | ALDH1A1 (0.45) | DAODDOPDE3BPDE3AALKBH3 | |
| SCHEMBL14317221 | 0.70 | ALDH1A1 (0.44) | DAODDOKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3349142 | 0.69 | ALDH1A1 (0.53) | PDE10ADAODDOKDM4EALDH1A1 | |
| SCHEMBL3345086 | 0.68 | ALKBH3 (0.42) | DAODDOALKBH3KDM4EALDH1A1 | |
| SCHEMBL3344690 | 0.68 | SMN1; SMN2 (0.49) | DAOPDE3BPDE3AALKBH3KDM4E | |
| SCHEMBL3349059 | 0.68 | ALDH1A1 (0.46) | DAOPDE3BPDE3AALKBH3KDM4E | |
| SCHEMBL3344710 | 0.68 | KDM4E (0.48) | DAOKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |