Sugi Predict

Sugi Predict / Compounds / SCHEMBL3343830

SCHEMBL3343830

SCHEMBL3343830

O=C(O)CSCCC(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 2/20 0.50
▸ HIF1A Q16665 1/20 0.50
▸ HSD17B10 Q99714 2/20 0.43
▸ GMNN O75496 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ THRB P10828 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ BLM P54132 1/20 0.43
▸ BHMT Q93088 1/20 0.39
▸ CYP2C19 P33261 1/20 0.38
▸ CES1 P23141 6/20 0.36
▸ MMP12 P39900 1/20 0.36
▸ MMP13 P45452 1/20 0.36
▸ MVD P53602 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ LMNA P02545 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9943878 0.86 GMNN (0.50) CYP2D6HIF1AHSD17B10GMNNTP53
SCHEMBL9943715 0.85 GMNN (0.53) CYP2D6HIF1AHSD17B10GMNNTP53
SCHEMBL9943764 0.83 GMNN (0.57) CYP2D6HIF1AHSD17B10GMNNTP53
SCHEMBL9943765 0.83 GMNN (0.57) CYP2D6HIF1AHSD17B10GMNNTP53
SCHEMBL9943488 0.82 CYP2D6 (0.46) CYP2D6HIF1AHSD17B10GMNNTP53
SCHEMBL2136528 0.81 CES1 (0.36) CES1KMT2AFAAHCES2PLA2G6
SCHEMBL7049566 0.79 LMNA (0.64) HSD17B10BHMTCYP2C19LMNAKMT2A
SCHEMBL1313188 0.76 CYP2D6 (0.73) CYP2D6HIF1AHSD17B10GMNNTP53
SCHEMBL24065889 0.76 CYP2D6 (0.39) CYP2D6HIF1AHSD17B10GMNNTP53
SCHEMBL24065950 0.76 CYP2D6 (0.39) CYP2D6HIF1AHSD17B10GMNNTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105732580-B Pesticidal compositions and methods related thereto 陶氏益农公司 2018-12-07 — — CN disclosed
CN-104822266-B Pesticidal compositions and methods related thereto 陶氏益农公司 2017-12-05 — — CN disclosed
US-20170267657-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2017-09-21 — — US disclosed
US-9708288-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-07-18 — — US disclosed
CN-104378986-B Pesticidal compositions and methods related thereto 陶氏益农公司 2017-05-31 — — CN disclosed
US-9591857-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-03-14 — — US disclosed
CN-105732580-A Pesticidal compositions and methods related thereto 陶氏益农公司 2016-07-06 — — CN disclosed
CN-105732579-A Pesticidal compositions and methods related thereto 陶氏益农公司 2016-07-06 — — CN disclosed
US-20160159766-A9 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-06-09 — — US disclosed
US-9282739-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2016-03-15 — — US disclosed
EP-2664613-A1 Process for producing amide compounds Sumitomo Chemical Company, Limited (JP) 2013-11-20 — — EP disclosed
EP-2662355-A1 Process for producing a (fluoroalkylthio) acetonitrile Sumitomo Chemical Company, Limited (JP) 2013-11-13 — — EP disclosed
US-20130291227-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2013-10-31 — — US disclosed
US-20130288893-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2013-10-31 — — US disclosed
WO-2013162716-A2 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2013-10-31 — — WO disclosed
WO-2013162715-A2 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2013-10-31 — — WO disclosed
WO-2013083568-A1 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS THAT CONTAIN SAID 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, AND USE THEREOF TO PRODUCE DRUGS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-06-13 — — WO disclosed
US-8247612-B2 Organic sulfur compound and its use for controlling harmful arthropod SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-21 — — US disclosed
EP-2465846-A1 PROCESS FOR PREPARATION OF (FLUOROALKYLTHIO)ACETIC ACID ESTERS Sumitomo Chemical Company, Limited (JP) 2012-06-20 — — EP disclosed
US-20100160430-A1 ORGANIC SULFUR COMPOUND AND ITS USE FOR CONTROLLING HARMFUL ARTHROPOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160159766-A9 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS CYP2D6 652/4885HIF1A 3604/4885HSD17B10 1414/4885
US-20130291227-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS CYP2D6 652/4885HIF1A 3604/4885HSD17B10 1414/4885
US-20100160430-A1 ORGANIC SULFUR COMPOUND AND ITS USE FOR CONTROLLING HARMFUL ARTHROPOD L3MBTL4, L3MBTL3, L3MBTL1 CYP2D6 2442/4885HIF1A 3587/4885HSD17B10 2464/4885
US-20170267657-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS CYP2D6 652/4885HIF1A 3604/4885HSD17B10 1414/4885
US-20130288893-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS CYP2D6 652/4885HIF1A 3604/4885HSD17B10 1414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.