Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790255 | 0.82 | ALDH1A1 (0.46) | KCNN4ALDH1A1ALOX15HDAC3HDAC4 | |
| SCHEMBL2466546 | 0.78 | ALDH1A1 (0.43) | KCNN4ALDH1A1ALOX15HDAC3HDAC4 | |
| SCHEMBL2470413 | 0.78 | ALDH1A1 (0.43) | KCNN4ALDH1A1ALOX15HDAC3HDAC4 | |
| SCHEMBL14086352 | 0.77 | KCNN4 (0.56) | KCNN4ALDH1A1ALOX15HDAC3HDAC4 | |
| SCHEMBL4538530 | 0.76 | MEN1 (0.60) | MAPK1LMNAKMT2ACYP2C19HIF1A | |
| SCHEMBL14916526 | 0.76 | ALDH1A1 (0.41) | KCNN4ALDH1A1ALOX15HDAC3HDAC4 | |
| SCHEMBL28556870 | 0.76 | KIF11 (0.47) | ALDH1A1ALOX15CYP3A4MAPK1MAPT | |
| SCHEMBL16667616 | 0.76 | ESR1 (0.42) | ALDH1A1HDAC4HDAC2HDAC8ESR1 | |
| SCHEMBL5049524 | 0.75 | SLC6A4 (0.41) | KCNN4ALDH1A1ALOX15HDAC3HDAC4 | |
| SCHEMBL27776663 | 0.75 | KCNN4 (0.59) | KCNN4ALDH1A1ALOX15HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109983128-A | Oligonucleotide composition and its method | 波涛生命科学有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-108135921-A | Oligonucleotide compositions and methods thereof | 波涛生命科学有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-108137492-A | Oligonucleotide compositions and methods thereof | 波涛生命科学有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-108025089-A | Oligonucleotide composition and its method | 波涛生命科学有限公司 | 2018-05-11 | — | — | CN | disclosed |
| US-20100105655-A1 | NOVEL COMPOUNDS 515 | ASTRAZENECA AB | 2010-04-29 | — | — | US | disclosed |
| US-7612197-B2 | Reacting a nucleophil with OH group with an electrophil to form an adduct, reacting adduct with a reagent selected from oxidizing, sulfurizing or selenizing agents to produce hydroxy protected oligonucleotide, heating to deprotect hydroxy protecting group such as 2-(2-pyridyl)aminoethoxycarbonyl | The United States of America as repesented by the Secretary of the Department of Health and Human Services (US) | 2009-11-03 | — | — | US | disclosed |
| US-20060281911-A1 | Thermolabile hydroxyl protecting groups and methods of use | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH (US) | 2006-12-14 | — | — | US | disclosed |
| WO-2004101582-A2 | THERMOLABILE HYDROXYL PROTECTING GROUPS AND METHODS OF USE | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-11-25 | — | — | WO | disclosed |
| EP-0881210-B1 | Process for the production of N,N-dialkylaminophenyl alkanols | CIBA SC HOLDING AG (CH) | 2001-11-21 | — | — | EP | disclosed |
| US-5962739-A | Process for the preparation of N,N- dialkylaminophenyl alkanols | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0881210-A1 | Process for the production of N,N-dialkylaminophenyl alkanols | Ciba SC Holding AG (CH) | 1998-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281911-A1 | Thermolabile hydroxyl protecting groups and methods of use | ADH1A, CYP2E1, ADH1C | KCNN4 1067/4885ALDH1A1 315/4885ALOX15 274/4885 |
| US-20100105655-A1 | NOVEL COMPOUNDS 515 | TYMS, ABCG2, UMPS | KCNN4 4521/4885ALDH1A1 649/4885ALOX15 1993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.