Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346289 | 0.88 | PDE5A (0.40) | FFAR4FFAR1FFAR2PTGDR2PPARD | |
| SCHEMBL3346056 | 0.83 | S1PR1 (0.41) | FFAR1PDE5APDE9ACACNA1C | |
| SCHEMBL3346903 | 0.77 | GRIN2B (0.36) | FFAR4PDE5APDE9A | |
| SCHEMBL3431063 | 0.76 | ALDH1A1 (0.39) | FFAR4CYP2C9 | |
| SCHEMBL3346086 | 0.76 | PTGER4 (0.44) | CYP2C9 | |
| SCHEMBL3431683 | 0.75 | RXRA (0.40) | FFAR4FFAR1FFAR2PDE5APDE9A | |
| SCHEMBL3347691 | 0.74 | FFAR4 (0.40) | FFAR4FFAR1PDE5A | |
| SCHEMBL3431568 | 0.73 | RXRA (0.44) | FFAR4FFAR1PTGDR2PDE5APDE9A | |
| SCHEMBL3431645 | 0.71 | RXRA (0.43) | FFAR4FFAR1PTGDR2PDE5APDE9A | |
| SCHEMBL3431483 | 0.71 | FFAR1 (0.43) | FFAR4FFAR1CTSAPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | disclosed |