SCHEMBL334875

SCHEMBL334875

CNS(=O)(=O)c1sccc1C(C)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 1/20 0.38
KMT2A Q03164 3/20 0.37
ACLY P53396 1/20 0.34
PTGS2 P35354 1/20 0.34
GAA P10253 3/20 0.33
KDM4E B2RXH2 2/20 0.33
POLB P06746 2/20 0.33
MAPK10 P53779 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPK1 P28482 2/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA3 P07451 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
CA5A P35218 2/20 0.33
CA7 P43166 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11485432 0.83 KMT2A (0.51) KMT2AKDM4EPOLBMAPK10SMN1; SMN2
SCHEMBL7508269 0.80 EDNRA (0.35) PTK2KMT2AACLYPTGS2MAPK10
SCHEMBL3585261 0.79 CA2 (0.42) PTK2KMT2AGAAKDM4EPOLB
SCHEMBL7555210 0.77 NPSR1 (0.58) PTK2KMT2AKDM4EPOLBSMN1; SMN2
SCHEMBL1436752 0.74 PTK2 (0.37) PTK2KMT2AKDM4EPOLBSMN1; SMN2
SCHEMBL4704966 0.74 MAPK1 (0.49) GAAKDM4EPOLBSMN1; SMN2ALDH1A1
SCHEMBL11482082 0.71 EDNRB (0.37) PTGS2GAASMN1; SMN2ALDH1A1CA12
SCHEMBL22021504 0.70 EDNRB (0.39) PTGS2GAASMN1; SMN2ALDH1A1CA12
SCHEMBL11481329 0.68 PKM (0.40) PTGS2GAASMN1; SMN2CA12CA1
SCHEMBL11473679 0.68 EDNRB (0.37) PTGS2GAASMN1; SMN2ALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250221408-A1 COMPOSITION EARTH CORPORATION (JP) 2025-07-10 US disclosed
CN-119114152-A Free radical generating catalyst, method for producing free radical, method for producing oxidation reaction product, pharmaceutical agent, and agricultural and livestock pharmaceutical agent 株式会社ACENET 2024-12-13 CN disclosed
EP-4473837-A1 COMPOSITION Earth Corporation (JP) 2024-12-11 EP disclosed
CN-118695780-A Composition and method for producing the same 阿斯制药株式会社 2024-09-24 CN disclosed
CN-110769931-B Free radical generating catalyst, method for producing free radical, method for producing oxidation reaction product, pharmaceutical agent, and agricultural and livestock pharmaceutical agent 株式会社ACENET 2024-09-17 CN disclosed
US-20240000084-A1 ANTIPATHOGENIC AGENT, ANTIBACTERIAL AGENT, ANTIVIRAL AGENT, PATHOGEN DISPOSAL DEVICE, ANTIPATHOGENIC AGENT PRODUCTION METHOD, ANTIBACTERIAL TREATMENT METHOD, VIRUS INACTIVATION METHOD, AND PATHOGEN DISPOSAL METHOD ACENET INC. (JP) 2024-01-04 US disclosed
CN-117281115-A Free radical generating catalyst, method for producing free radical, method for producing oxidation reaction product, pharmaceutical agent, and agricultural and livestock pharmaceutical agent 株式会社ACENET 2023-12-26 CN disclosed
WO-2023190598-A1 COMPOSITION アース製薬株式会社 2023-10-05 WO disclosed
US-20230263710-A1 ORAL CARE AGENT OSAKA UNIVERSITY (JP) 2023-08-24 US disclosed
EP-4230042-A1 ANTIPATHOGENIC DRUG, ANTIBACTERIAL AGENT, ANTIVIRAL AGENT, PATHOGEN PROCESSING DEVICE, METHOD FOR PRODUCING ANTIPATHOGENIC DRUG, ANTIBACTERIAL METHOD, VIRUS INACTIVATION METHOD, AND PATHOGEN PROCESSING METHOD Acenet Inc. (JP) 2023-08-23 EP disclosed
EP-0527801-B1 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANHYDRASE INHIBITORS ALCON LAB INC (US) 2002-07-31 EP disclosed
EP-1206265-A1 SRC KINASE INHIBITOR COMPOUNDS Merck & Co., Inc. (US) 2002-05-22 EP disclosed
US-6362231-B1 MODULATOR OF PARATHYROID HORMONE; OSTEOPOROSIS NPS PHARMACEUTICALS, INC. 2002-03-26 US disclosed
WO-2001000213-A1 SRC KINASE INHIBITOR COMPOUNDS MERCK & CO., INC. (US) 2001-01-04 WO disclosed
EP-0933354-A1 CALCIUM RECEPTOR-ACTIVE COMPOUNDS KIRIN BEER KABUSHIKI KAISHA (JP) 1999-08-04 EP disclosed
US-5240923-A Treating glaucoma ALCON LABORATORIES, INC. (US) 1993-08-31 US disclosed
EP-0527801-A4 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS 1993-03-10 EP disclosed
EP-0527801-A1 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS ALCON LABORATORIES, INC. (US) 1993-02-24 EP disclosed
US-5153192-A For controlling intraocular pressure ALCON LABORATORIES, INC. (US) 1992-10-06 US disclosed
WO-1991015486-A1 THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS ALCON LABORATORIES, INC. (US) 1991-10-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230263710-A1 ORAL CARE AGENT TAS2R39, TAS2R40, TAS2R45 PTK2 2478/4885KMT2A 476/4885ACLY 2566/4885
US-20240000084-A1 ANTIPATHOGENIC AGENT, ANTIBACTERIAL AGENT, ANTIVIRAL AGENT, PATHOGEN DISPOSAL DEVICE, ANTIPATHOGENIC AGENT PRODUCTION METHOD, ANTIBACTERIAL TREATMENT METHOD, VIRUS INACTIVATION METHOD, AND PATHOGEN DISPOSAL METHOD EIF2AK2, HAO2, ZC3HAV1 PTK2 3276/4885KMT2A 2886/4885ACLY 2615/4885
US-20250221408-A1 COMPOSITION GGPS1, PGGT1B, HBG2 PTK2 1524/4885KMT2A 4792/4885ACLY 3474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.