SCHEMBL797850

SCHEMBL797850

CN(CC(=O)O)c1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.43
CAMK2A Q9UQM7 1/20 0.43
APP P05067 1/20 0.39
ESR1 P03372 3/20 0.39
ESR2 Q92731 2/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 1/20 0.39
CA12 O43570 4/20 0.39
CA1 P00915 4/20 0.39
CA9 Q16790 4/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
CA3 P07451 1/20 0.38
TYR P14679 1/20 0.38
DRD1 P21728 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA14 Q9ULX7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1961276 0.98 CA2 (0.42) CA2CAMK2AAPPESR1ESR2
SCHEMBL3348892 0.83 KEAP1 (0.54) CA2ALDH1A1CA12CA1CA9
SCHEMBL196635 0.83 KMT2A (0.49) CA2ALDH1A1CYP3A4CA12CA9
SCHEMBL5726224 0.82 TDP1 (0.46) CA2ALDH1A1CYP3A4CA12CA1
SCHEMBL10906215 0.82 ALDH1A1 (0.57) CA2ALDH1A1CA12CA1CA9
SCHEMBL8541381 0.82 ALDH1A1 (0.45) ALDH1A1CYP3A4KEAP1NFE2L2L3MBTL1
SCHEMBL3349309 0.82 MAPT (0.41) CA2ALDH1A1CA12CA1CA9
SCHEMBL9632043 0.82 TPMT (0.40) CA2APPALDH1A1CA12CA1
SCHEMBL14364107 0.82 SLC6A9 (0.40) CA2APPALDH1A1CA12CA1
SCHEMBL3763384 0.82 NPC1 (0.50) CA2ALDH1A1CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116334054-A Penicillin G acylase mutant 上海邦林生物科技有限公司 2023-06-27 CN claimed
CN-111116463-A Method for synthesizing cefpiramide side chain acid 山东鑫泉医药有限公司 2020-05-08 CN claimed
US-5013550-A Antibiotics called \"chloropolysporins B and C\", a process for their preparation, and their therapeutic and veterinary use SANKYO COMPANY LIMITED (JP) 1991-05-07 US claimed
US-4918054-A Glycopeptide antibiotic SANKYO COMPANY LIMITED (JP) 1990-04-17 US claimed
EP-0187722-A2 Antibiotics called \"chloropolysporins B and C\", a process for their preparation, and their therapeutic and veterinary use SANKYO COMPANY LIMITED (JP) 1986-07-16 EP claimed
CN-120699943-B Penicillin acylase for synthesizing beta-lactam antibiotics 浙江师范大学行知学院 2026-05-15 CN disclosed
CN-119242757-B Method for separating amoxicillin and phenylacetic acid from reaction liquid for preparing amoxicillin by enzyme catalysis one-step method 浙江师范大学行知学院 2025-05-16 CN disclosed
CN-118995868-B Method for synthesizing amoxicillin from penicillin or salt thereof by enzyme catalysis one-step method 浙江师范大学行知学院 2025-03-28 CN disclosed
CN-119242757-A Method for separating amoxicillin and phenylacetic acid from reaction liquid for preparing amoxicillin by enzyme catalysis one-step method 浙江师范大学行知学院 2025-01-03 CN disclosed
CN-119020335-A Penicillin acylase mutant and application thereof 浙江师范大学行知学院 2024-11-26 CN disclosed
CN-118995868-A Method for synthesizing amoxicillin from penicillin or salt thereof by enzyme catalysis one-step method 浙江师范大学行知学院 2024-11-22 CN disclosed
CN-118667913-A Preparation method of cefprozil mother nucleus APCA 苏州盛达药业有限公司 2024-09-20 CN disclosed
CN-108872436-B Method for analyzing content of D (-) p-hydroxyphenylglycine in D (-) p-hydroxyphenylglycine methyl ester 山东普洛汉兴医药有限公司 2021-08-03 CN disclosed
CN-111116463-A Method for synthesizing cefpiramide side chain acid 山东鑫泉医药有限公司 2020-05-08 CN disclosed
CN-103209700-A Broad spectrum antibiotic Arylomycin analogs SCRIPPS RESEARCH INST 2013-07-17 CN disclosed
US-5013550-A Antibiotics called \"chloropolysporins B and C\", a process for their preparation, and their therapeutic and veterinary use SANKYO COMPANY LIMITED (JP) 1991-05-07 US disclosed
US-4918054-A Glycopeptide antibiotic SANKYO COMPANY LIMITED (JP) 1990-04-17 US disclosed
US-4742045-A ANIMAL FEED SMITHKLINE BECKMAN CORPORATION (US) 1988-05-03 US disclosed
EP-0255299-A2 Glycopeptide antibiotics SMITHKLINE BEECHAM CORPORATION (US) 1988-02-03 EP disclosed
EP-0187722-A2 Antibiotics called \"chloropolysporins B and C\", a process for their preparation, and their therapeutic and veterinary use SANKYO COMPANY LIMITED (JP) 1986-07-16 EP disclosed