Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | HTR7 | P34969 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3356566 | 0.90 | HTR2A (0.48) | DRD2SLC6A4HTR1AHTR2AHTR7 | |
| SCHEMBL3351511 | 0.90 | HTR1A (0.41) | DRD2HTR1AHTR1BHTR1FHTR2A | |
| SCHEMBL3349663 | 0.85 | HTR1B (0.54) | HTR1AHTR1BHTR1FSCDALOX15 | |
| SCHEMBL3369338 | 0.82 | PIK3CD (0.43) | HTR1AHTR1BHTR1FSCD | |
| SCHEMBL13537309 | 0.82 | HTR1A (0.42) | DRD2SLC6A4HTR1AHTR1BHTR1F | |
| SCHEMBL3349251 | 0.80 | LMNA (0.44) | DRD2SLC6A4HTR1AHTR1BHTR1F | |
| SCHEMBL30778591 | 0.80 | KDM4E (0.43) | HTR1AHTR1BHTR1FROCK1SCD | |
| SCHEMBL3352822 | 0.80 | HTR1A (0.41) | HTR1AHTR1BHTR1FGPR119SCD | |
| SCHEMBL3352334 | 0.80 | HTR2A (0.45) | DRD2HTR2AHTR7KCNH2GPR119 | |
| SCHEMBL3351612 | 0.78 | OGFRL1 (0.40) | HTR1AHTR1BHTR1FSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |