Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596296 | 0.88 | ALDH1A1 (0.47) | LMNAALDH1A1GAASMN1; SMN2VCAM1 | |
| SCHEMBL12996890 | 0.88 | ALDH1A1 (0.47) | LMNAALDH1A1GAASMN1; SMN2VCAM1 | |
| SCHEMBL3354484 | 0.82 | ALDH1A1 (0.41) | LMNAALDH1A1SMN1; SMN2ACHEVCAM1 | |
| SCHEMBL3357241 | 0.82 | ACHE (0.41) | LMNAALDH1A1ACHEMAPTHIF1A | |
| SCHEMBL3355435 | 0.81 | ALDH1A1 (0.42) | LMNAALDH1A1SMN1; SMN2ACHEMAPT | |
| SCHEMBL28587259 | 0.80 | XDH (0.53) | LMNAALDH1A1GAASMN1; SMN2VCAM1 | |
| SCHEMBL3350475 | 0.80 | KDM1A (0.40) | — | |
| SCHEMBL3354325 | 0.80 | AVPR1A (0.43) | LMNAALDH1A1GAASMN1; SMN2ACHE | |
| SCHEMBL3355907 | 0.80 | ACHE (0.39) | ALDH1A1ACHEMAPTHIF1AAPP | |
| SCHEMBL3358236 | 0.79 | ALDH1A1 (0.47) | LMNAALDH1A1GAASMN1; SMN2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |