SCHEMBL3351157

SCHEMBL3351157

CC(C)(C)OC(=O)N(CC(=O)O)c1ccsc1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 9/20 0.40
CHRM1 P11229 9/20 0.40
CHRM3 P20309 9/20 0.40
GSTO1 P78417 1/20 0.37
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
F2 P00734 1/20 0.33
SLC6A9 P48067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5898287 1.00 CHRM2 (0.40) CHRM2CHRM1CHRM3GSTO1CTSS
SCHEMBL219603 0.80 SMN1; SMN2 (0.49) GSTO1F2
SCHEMBL895556 0.78 MLYCD (0.39)
SCHEMBL21422867 0.77 PAX8 (0.44) CHRM2CHRM1CHRM3CTSSCTSK
SCHEMBL2929114 0.77 MLYCD (0.38) CTSSCTSK
SCHEMBL11648528 0.77 MLYCD (0.38)
SCHEMBL3349318 0.77 MLYCD (0.41)
SCHEMBL3375082 0.77 MLYCD (0.38)
SCHEMBL266144 0.77 MT-CO2 (0.46)
SCHEMBL7341628 0.76 CHRM2 (0.34) CHRM2CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137643-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL SOC DES PRODUITS NESTLE S A (CH) 2026-05-21 US claimed
US-12539288-B2 Compositions and methods using at least one glycine or derivative thereof and/or at least one N-acetylcysteine or derivative thereof, and at least one thymol and/or carvacrol SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-02-03 US claimed
US-20250281438-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL SOCIETE DES PRODUITS NESTLE S.A. (CH) 2025-09-11 US claimed
EP-4440563-A1 COMPOSITIONS AND METHODS USING AN AMINO ACID BLEND FOR PROVIDING A HEALTH BENEFIT IN AN ANIMAL Société des Produits Nestlé S.A. (CH) 2024-10-09 EP claimed
CN-118338897-A Compositions and methods for providing health benefits in animals using amino acid blends 雀巢产品有限公司 2024-07-12 CN claimed
US-11974975-B2 Compositions and methods using at least one glycine or derivative thereof, at least one N-acetylcysteine or derivative thereof, and at least one nicotinamide riboside or NAD+ precursor SOCIETE DES PRODUITS NESTLE S.A. (CH) 2024-05-07 US claimed
US-20240100006-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND AT LEAST ONE LARGE NEUTRAL AMINO ACID AND/OR CATIONIC AMINO ACID OR PRECURSOR THEREOF SOCIETE DES PRODUITS NESTLE S.A. (CH) 2024-03-28 US claimed
US-20240091186-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF, AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE NICOTINAMIDE RIBOSIDE OR NAD+ PRECURSOR SOCIETE DES PRODUITS NESTLE S.A. (CH) 2024-03-21 US claimed
EP-4262776-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL Société des Produits Nestlé S.A. (CH) 2023-10-25 EP claimed
EP-4259120-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND AT LEAST ONE LARGE NEUTRAL AMINO ACID AND/OR CATIONIC AMINO ACID OR PRECURSOR THEREOF Société des Produits Nestlé S.A. (CH) 2023-10-18 EP claimed
US-20220000820-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF, AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE NICOTINAMIDE RIBOSIDE OR NAD+ PRECURSOR SOCIETE DES PRODUITS NESTLE S.A. (CH) 2022-01-06 US claimed
WO-2021232041-A1 N-ACETYLCYSTEINE AND GLYCINE FOR TREATMENT OF COVID-19 AND POST COVID-19 SYMPTOMS BAYLOR COLLEGE OF MEDICINE (US) 2021-11-18 WO claimed
US-20210244696-A1 BENEFITS OF SUPPLEMENTATION WITH N-ACETYLCYSTEINE AND GLYCINE TO IMPROVE GLUTATHIONE LEVELS BAYLOR COLLEGE OF MEDICINE 2021-08-12 US claimed
EP-3855943-A2 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF, AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE NICOTINAMIDE RIBOSIDE OR NAD+ PRECURSOR Société des Produits Nestlé S.A. (CH) 2021-08-04 EP claimed
CN-112654264-A Using at least one glycine or derivative thereof, at least one N-acetylcysteine or derivative thereof, and at least one nicotinamide riboside or NAD+Composition and method of precursors 雀巢产品有限公司 2021-04-13 CN claimed
US-10952982-B2 Benefits of supplementation with N-acetylcysteine and glycine to improve glutathione levels SOCIETE DES PRODUITS NESTLE S.A. (CH) 2021-03-23 US claimed
WO-2020064946-A2 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF, AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE NICOTINAMIDE RIBOSIDE OR NAD+ PRECURSOR Société des Produits Nestlé S.A. (CH) 2020-04-02 WO claimed
US-20180161297-A1 BENEFITS OF SUPPLEMENTATION WITH N-ACETYLCYSTEINE AND GLYCINE TO IMPROVE GLUTATHIONE LEVELS Société des Produits Nestlé S.A. (CH) 2018-06-14 US claimed
EP-3302459-A1 BENEFITS OF SUPPLEMENTATION WITH N-ACETYLCYSTEINE AND GLYCINE TO IMPROVE GLUTATHIONE LEVELS Baylor College of Medicine (US) 2018-04-11 EP claimed
WO-2016191468-A1 BENEFITS OF SUPPLEMENTATION WITH N-ACETYLCYSTEINE AND GLYCINE TO IMPROVE GLUTATHIONE LEVELS BAYLOR COLLEGE OF MEDICINE (US) 2016-12-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539288-B2 Compositions and methods using at least one glycine or derivative thereof and/or at least one N-acetylcysteine or derivative thereof, and at least one thymol and/or carvacrol LIPC, GGT1, TGM2 CHRM2 2058/4885CHRM1 1857/4885CHRM3 2091/4885
US-20260137643-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL LIPC, GGT1, TGM2 CHRM2 1877/4885CHRM1 1728/4885CHRM3 1983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.