Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856362 | 0.74 | GABRA1 (0.41) | MEN1POLBKMT2AATMDPP4 | |
| Hydrochloric Acid SCHEMBL3355962 | 0.74 | SIGMAR1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL819620 | 0.67 | GABRA1 (0.52) | KMT2ADPP4SLC6A2 | |
| Hydrochloric Acid SCHEMBL3201535 | 0.66 | ADRA2A (0.35) | MEN1POLBKMT2AATMDPP4 | |
| SCHEMBL4022049 | 0.65 | HTR2A (0.46) | MEN1POLBKMT2AGPR3HTR2A | |
| Hydrochloric Acid SCHEMBL3192580 | 0.65 | MAPT (0.33) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3260463 | 0.65 | GPR3 (0.33) | MEN1POLBKMT2AATMGPR3 | |
| SCHEMBL21064361 | 0.64 | GABRA1 (0.45) | MEN1POLBKMT2AATMDPP4 | |
| SCHEMBL17024335 | 0.64 | DPP4 (0.37) | MEN1POLBKMT2AATMDPP4 | |
| Hydrochloric Acid SCHEMBL715077 | 0.64 | DPP4 (0.37) | MEN1POLBKMT2AATMDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410231-B2 | Production process of olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20100029868-A1 | PRODUCTION PROCESS OF OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-04 | — | — | US | disclosed |
| WO-2007023618-A1 | HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-01 | — | — | WO | disclosed |