Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30724641 | 0.82 | GABRA1 (0.39) | SIGMAR1 | |
| SCHEMBL6399753 | 0.77 | SIGMAR1 (0.38) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3352101 | 0.74 | MEN1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL3211462 | 0.70 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL28755427 | 0.69 | NPC1 (0.33) | SIGMAR1 | |
| SCHEMBL7778428 | 0.69 | PNMT (0.35) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3205744 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL3259462 | 0.69 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL5158379 | 0.68 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL27520400 | 0.66 | SIGMAR1 (0.33) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013047891-A2 | WASHING METHOD, ADDITION POLYMERIZATION METHOD, PREPOLYMERIZATION METHOD, PREPOLYMERIZED CATALYTIC COMPONENT FOR ADDITION POLYMERIZATION, AND METHOD FOR PRODUCING ADDITION POLYMER USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-04-04 | — | — | WO | disclosed |
| US-8410231-B2 | Production process of olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20100029868-A1 | PRODUCTION PROCESS OF OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-04 | — | — | US | disclosed |
| WO-2007023618-A1 | HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-01 | — | — | WO | disclosed |