Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344258 | 0.88 | KDM4E (0.43) | NR1D1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL3430772 | 0.84 | KDM4E (0.38) | KDM4EHSD17B10MAPTHPGDTRPV1 | |
| SCHEMBL3352922 | 0.83 | GSK3B (0.38) | PIM1PIM2GSK3BPTGES | |
| SCHEMBL3428421 | 0.80 | PPARD (0.39) | PIM1PIM2GSK3BPTGES | |
| SCHEMBL3430136 | 0.76 | DHODH (0.39) | KDM4EHSD17B10MAPTHPGDTRPV1 | |
| SCHEMBL3432976 | 0.69 | GSK3B (0.39) | KDM4EHSD17B10MAPTHPGDTRPV1 | |
| SCHEMBL3476248 | 0.68 | NR1D1 (0.41) | NR1D1KIF11TRPV1KDM5A | |
| SCHEMBL3430623 | 0.66 | FFAR1 (0.43) | KDM4EHSD17B10HPGD | |
| SCHEMBL3476576 | 0.64 | TRPV1 (0.50) | KIF11TRPV1PIM1PIM2GSK3B | |
| SCHEMBL3346362 | 0.63 | DHODH (0.39) | KDM4EHSD17B10TRPV1TSHRABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | claimed |