Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 15/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27580388 | 0.86 | ALOX15 (0.49) | ALOX15F7F3F9 | |
| SCHEMBL335834 | 0.85 | RAB9A (0.42) | — | |
| SCHEMBL336443 | 0.84 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL336047 | 0.84 | POLB (0.43) | F7F3F9 | |
| SCHEMBL335498 | 0.84 | TAS1R3 (0.45) | F7F3F9 | |
| SCHEMBL334843 | 0.83 | KDR (0.45) | F7F9 | |
| SCHEMBL15282212 | 0.81 | ACP1 (0.46) | F7F3 | |
| SCHEMBL15282285 | 0.81 | ACP1 (0.46) | F7F3 | |
| SCHEMBL335500 | 0.81 | F9 (0.44) | F7F9 | |
| SCHEMBL336367 | 0.80 | MAPT (0.47) | F7F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |