Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355352 | 0.99 | ADRB2 (0.47) | HTR1DADRB2HTR2AHTR6GAA | |
| SCHEMBL3356705 | 0.90 | HTR1D (0.47) | HTR1DADRB2HTR2AHTR6SIGMAR1 | |
| SCHEMBL2075509 | 0.89 | HTR2A (0.44) | HTR1DADRB2HTR2AHTR6GAA | |
| SCHEMBL3354205 | 0.88 | LMNA (0.46) | HTR1DADRB2HTR2AHTR6SIGMAR1 | |
| SCHEMBL3353571 | 0.87 | ACHE (0.51) | HTR1DADRB2GAAACHE | |
| SCHEMBL3350921 | 0.86 | ACHE (0.50) | HTR1DADRB2ACHE | |
| SCHEMBL3320875 | 0.82 | HTR1D (0.68) | HTR1DADRB2HTR2AHTR6 | |
| SCHEMBL32669268 | 0.81 | ADRB2 (0.67) | ADRB2HTR2AHTR6HRH3 | |
| SCHEMBL13537395 | 0.80 | HTR6 (0.43) | HTR1DADRB2HTR2AHTR6GAA | |
| SCHEMBL13537252 | 0.79 | HTR6 (0.44) | HTR1DADRB2HTR2AHTR6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |