Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531640 | 0.83 | HTR2A (0.43) | KDM4EALDH1A1SMN1; SMN2ALOX15OPRM1 | |
| SCHEMBL3352228 | 0.77 | HTR7 (0.44) | MAPTALDH1A1HRH4OPRM1OPRL1 | |
| SCHEMBL21983722 | 0.77 | HTR6 (0.34) | MAPTCYP11B1CYP11B2 | |
| SCHEMBL3351951 | 0.76 | NOTUM (0.40) | KDM4EALDH1A1HTR1DHTR1BHRH4 | |
| SCHEMBL13841063 | 0.75 | OPRM1 (0.34) | OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL3352865 | 0.75 | HTR1D (0.51) | HTR1DHTR1BGAASMN1; SMN2OPRM1 | |
| SCHEMBL21983714 | 0.73 | CYP11B2 (0.43) | MAPTALDH1A1TDP1CYP11B1CYP11B2 | |
| SCHEMBL3349663 | 0.72 | HTR1B (0.54) | HTR1DHTR1BGAASMN1; SMN2ALOX15 | |
| SCHEMBL30594683 | 0.72 | PRKCI (0.51) | HTR1DHTR1BGAASMN1; SMN2BRPF1 | |
| SCHEMBL2266494 | 0.72 | PRKCI (0.51) | HTR1DHTR1BGAASMN1; SMN2BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |