Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355435 | 0.90 | ALDH1A1 (0.42) | ACHEPKMMAPTAPPBCHE | |
| SCHEMBL3357241 | 0.82 | ACHE (0.41) | ACHEPKMMAPTAPPBCHE | |
| SCHEMBL3354484 | 0.82 | ALDH1A1 (0.41) | ACHEPKMMAPTSIRT6HIF1A | |
| SCHEMBL3354823 | 0.80 | LMNA (0.43) | ACHEMAPTAPPBCHESIRT6 | |
| SCHEMBL3354325 | 0.80 | AVPR1A (0.43) | ACHEPKMMAPTHIF1AHTR7 | |
| SCHEMBL13537256 | 0.79 | OPRM1 (0.38) | — | |
| SCHEMBL3358236 | 0.79 | ALDH1A1 (0.47) | ACHEHIF1AALDH1A1 | |
| SCHEMBL3352685 | 0.77 | MAPT (0.47) | ACHEMAPTAPPBCHESIRT6 | |
| SCHEMBL3357600 | 0.77 | ACHE (0.42) | ACHEPKMHIF1AALDH1A1 | |
| SCHEMBL3348558 | 0.76 | MAPT (0.39) | ACHEPKMMAPTSIRT6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |