Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354104 | 0.88 | DRD2 (0.60) | HTR7DRD2SLC6A4HTR1AHTR1D | |
| SCHEMBL3358021 | 0.85 | HTR7 (0.47) | HTR7DRD2SLC6A4HTR1AHTR1D | |
| SCHEMBL3353280 | 0.84 | HTR7 (0.53) | HTR7DRD2SLC6A4HTR1AHTR1D | |
| SCHEMBL3354706 | 0.83 | ALDH1A1 (0.44) | HTR7DRD2SLC6A4HTR1AHTR1D | |
| SCHEMBL3358927 | 0.81 | DRD2 (0.50) | HTR7DRD2SLC6A4HTR1AHTR1D | |
| SCHEMBL7805698 | 0.80 | HTR7 (0.45) | HTR7DRD2SLC6A4ALDH1A1OPRM1 | |
| SCHEMBL13537339 | 0.80 | DRD2 (0.47) | HTR7DRD2SLC6A4HTR1AHTR1D | |
| SCHEMBL12253684 | 0.80 | HTR7 (0.55) | HTR7DRD2SLC6A4HTR1AHTR1D | |
| SCHEMBL7798214 | 0.79 | ACHE (0.59) | DRD2MEN1KMT2AACHE | |
| SCHEMBL3355827 | 0.79 | HTR7 (0.42) | HTR7DRD2SLC6A4HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |