Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355548 | 0.90 | HTR1D (0.48) | HTR1DADRB2HTR6HTR2ASIGMAR1 | |
| SCHEMBL3355352 | 0.89 | ADRB2 (0.47) | HTR1DADRB2HTR6HTR2ASIGMAR1 | |
| SCHEMBL3352639 | 0.87 | NR1H2 (0.53) | ADRB2HTR6NR1H2LMNACYP2D6 | |
| SCHEMBL3354205 | 0.86 | LMNA (0.46) | HTR1DADRB2HTR6HTR2ALMNA | |
| SCHEMBL3320875 | 0.81 | HTR1D (0.68) | HTR1DADRB2HTR6HTR2AHTT | |
| SCHEMBL13537326 | 0.80 | HTR6 (0.44) | HTR1DADRB2HTR6MPOCYP1A2 | |
| SCHEMBL12850610 | 0.80 | HTR2A (0.59) | HTR6HTR2ALMNATSHRHTT | |
| SCHEMBL2075509 | 0.79 | HTR2A (0.44) | HTR1DADRB2HTR6HTR2ASIGMAR1 | |
| SCHEMBL3351522 | 0.78 | HTR6 (0.51) | HTR6LMNACYP2D6 | |
| SCHEMBL3353571 | 0.77 | ACHE (0.51) | HTR1DADRB2NR1H2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |