Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | MMP13 | P45452 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336155 | 0.83 | TAS1R3 (0.45) | MMP2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL15282285 | 0.81 | ACP1 (0.46) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL15282212 | 0.81 | ACP1 (0.46) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL335390 | 0.81 | ABL1 (0.44) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL336367 | 0.80 | MAPT (0.47) | NPC1RAB9ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL335834 | 0.80 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL335948 | 0.80 | ABL1 (0.45) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL335286 | 0.79 | ACP1 (0.42) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL335576 | 0.79 | ABL1 (0.43) | NPC1RAB9ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL335351 | 0.79 | EGFR (0.50) | NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |