SCHEMBL3359903

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3360010	0.88	CALM1 (0.55)	CALM1IDH1L3MBTL1PLA2G10PLA2G2A
	SCHEMBL477648	0.83	HTR2A (0.56)	IGF1RSLC6A2SLC6A4SLC6A3HTR2A
	SCHEMBL3858148	0.83	HTR2A (0.56)	IGF1RSLC6A2SLC6A4SLC6A3HTR2A
	SCHEMBL1005021	0.83	CALM1 (0.67)	CALM1HTR2AIDH1L3MBTL1PLA2G10
	SCHEMBL10689961	0.81	IGF1R (0.48)	IGF1RCNR2SLC6A2SLC6A4SLC6A3
	SCHEMBL13016669	0.81	CALM1 (0.46)	IGF1RCNR2SLC6A2SLC6A4SLC6A3
	SCHEMBL2268223	0.78	CYP2A6 (0.50)	SLC6A2SLC6A4SLC6A3HTR2ACNR1
	SCHEMBL10439663	0.78	MAOB (0.42)	SLC6A2SLC6A4SLC6A3EPHX1
	SCHEMBL11642923	0.78	ALDH1A1 (0.65)	SLC6A2SLC6A4SLC6A3HTR2ANPC1
	SCHEMBL9503931	0.77	CALM1 (0.57)	CALM1IDH1PLA2G10PLA2G2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.