SCHEMBL3433459

SCHEMBL3433459

CC(CC(NC(=O)c1cc(=O)[nH]c(=O)[nH]1)C(=O)O)NC(=N)N

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.41
ALDH1A1 P00352 2/20 0.39
LMNA P02545 2/20 0.39
CYP1A2 P05177 1/20 0.39
GRN P28799 2/20 0.36
SORT1 Q99523 2/20 0.36
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
ALB P02768 3/20 0.35
IL2 P60568 3/20 0.35
UBASH3B Q8TF42 1/20 0.35
AKR1B1 P15121 2/20 0.34
CA2 P00918 2/20 0.34
CA1 P00915 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360046 0.84 GRN (0.51) GPR84ALDH1A1LMNACYP1A2GRN
SCHEMBL21185729 0.76 ALDH1A1 (0.49) GPR84ALDH1A1LMNACYP1A2KMT2A
SCHEMBL3434998 0.76 GPR84 (0.45) GPR84ALDH1A1KDM4EALBIL2
SCHEMBL11979054 0.74 LMNA (0.53) GPR84ALDH1A1LMNACYP1A2KMT2A
SCHEMBL28577021 0.74 KDM4E (0.47) GPR84ALDH1A1LMNACYP1A2KDM4E
SCHEMBL21185586 0.74 KDM4E (0.47) GPR84ALDH1A1LMNACYP1A2KDM4E
Hydrochloric Acid SCHEMBL28578292 0.73 KDM4E (0.46) GPR84ALDH1A1LMNACYP1A2KDM4E
SCHEMBL3888955 0.72 PYGL (0.59) GPR84ALDH1A1KDM4EALBIL2
SCHEMBL3434869 0.72 LMNA (0.50) GPR84ALDH1A1LMNACYP1A2KMT2A
SCHEMBL3433136 0.70 GPR84 (0.49) GPR84ALDH1A1LMNACYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236952-B2 Preparations containing amino acids and orotic acid Northern Innovations Holding Corp. (CA) 2012-08-07 US disclosed
EP-2231622-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID Northern Innovations and Formulations Corp. (CA) 2010-09-29 EP disclosed
WO-2009076743-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID IOVATE T. & P. INC. (CA) 2009-06-25 WO disclosed
US-20090156812-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID IOVATE T. & P. INC. (CA) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156812-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID DDC, ODC1, OTC GPR84 3114/4885ALDH1A1 2765/4885LMNA 4516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.