Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 8/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 8/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 7/20 | 0.41 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.41 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31462462 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10SIGMAR1KCNJ6 | |
| SCHEMBL23748795 | 0.98 | KDM4E (0.46) | ALDH1A1KDM4EHSD17B10SIGMAR1KCNJ6 | |
| SCHEMBL15935405 | 0.90 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EHSD17B10SIGMAR1SMN1; SMN2 | |
| SCHEMBL28720539 | 0.82 | SMN1; SMN2 (0.38) | ALDH1A1KDM4EHSD17B10SIGMAR1SMN1; SMN2 | |
| SCHEMBL15832226 | 0.81 | SIGMAR1 (0.43) | ALDH1A1KDM4ESIGMAR1KCNJ6KCNJ3 | |
| SCHEMBL6525498 | 0.81 | KDM4E (0.46) | ALDH1A1KDM4EHSD17B10KCNJ6KCNJ3 | |
| SCHEMBL1695102 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EHSD17B10KCNJ6KCNJ3 | |
| SCHEMBL13135665 | 0.81 | ALOX15 (0.51) | SIGMAR1SMN1; SMN2KDM5A | |
| SCHEMBL19300056 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10SIGMAR1KCNJ6 | |
| SCHEMBL854311 | 0.81 | KDM4E (0.46) | ALDH1A1KDM4EHSD17B10KCNJ6KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004802-A | Method for synthesizing N-alkyl substituted 3, 5-dimethylpyrazole compound by one-pot method | 四川轻化工大学 | 2025-05-16 | — | — | CN | disclosed |
| EP-3863711-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |
| CN-108779099-B | Piperidine derivatives and methods of use thereof | 维特卫治疗有限责任公司 | 2020-11-17 | — | — | CN | disclosed |
| EP-3423447-B1 | PIPERIDINE DERIVATIVE AND METHODS OF USE THEREOF | VTV THERAPEUTICS LLC (US) | 2020-03-25 | — | — | EP | disclosed |
| US-10364233-B2 | Piperidine derivative and methods of use thereof | VTV THERAPEUTICS LLC (US) | 2019-07-30 | — | — | US | disclosed |
| EP-3423447-A1 | PIPERIDINE DERIVATIVE AND METHODS OF USE THEREOF | vTv Therapeutics LLC (US) | 2019-01-09 | — | — | EP | disclosed |
| US-20180362505-A1 | Piperidine Derivative and Methods of Use Thereof | VTV THERAPEUTICS LLC | 2018-12-20 | — | — | US | disclosed |
| US-7968573-B2 | Hydrazide compound and pesticidal use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-28 | — | — | US | disclosed |
| US-20110071291-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | IKEGAMI HIROSHI | 2011-03-24 | — | — | US | disclosed |
| US-7691931-B2 | Organic-inorganic hybrid material and method of preparing the organic-inorganic hybrid material, and electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method using the organic-inorganic hybrid material | RICOH COMPANY LTD. (JP) | 2010-04-06 | — | — | US | disclosed |
| US-6066428-A | PHOTOCONDUCTOR COMPRISING ELECTROCONDUCTIVE SUPPORT WITH PHOTOCONDUCTIVE LAYER COMPRISING AROMATIC POLYCARBONATE RESIN HAVING CHARGE TRANSPORT PROPERTIES | RICOH COMPANY, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| US-6045959-A | CHARGE TRANSPORTING POLYMER | RICOH COMPANY, LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| US-6027846-A | HIGH PHOTOSENSITIVITY, HIGH DURABILITY | RICOH COMPANY, LTD. (JP) | 2000-02-22 | — | — | US | disclosed |
| US-6018014-A | PRESCRIBED DIOL MONOMER HAS STRUCTURE HYDROXY-(ARYLENE)-(2-(AMINOARYL OR HETEROCYCLE)VINYL)-(ARYLENE)-HYDROXYL;USEFUL FOR A CHARGE-TRANSPORT POLYMER MATERIAL FOR AN ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEDIUM | RICOH COMPANY, LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| US-5976746-A | ELECTROCONDUCTIVE SUPPORT; PHOTOCONDUCTIVE LAYER | RICOH COMPANY, LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5840454-A | Aromatic polycarbonate and electrophotographic photosensitive medium using same | RICOH COMPANY, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0600447-B1 | Aromatic polycarbonate and production method thereof | MITSUI CHEMICALS INC (JP) | 1998-10-07 | — | — | EP | disclosed |
| US-5426170-A | Interfacial polymerization of aromatic dihydroxy compound, carbonate precursor, alkali metal or alkaline metal base, water and solvent, endcapping | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-06-20 | — | — | US | disclosed |
| EP-0600447-A2 | Aromatic polycarbonate and production method thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1994-06-08 | — | — | EP | disclosed |
| US-4286084-A | INTERFACIAL POLYMERIZATION USING PROMOTERS TO FORM HIGH-MOLECULAR-WEIGHT POLYMERS | GENERAL ELECTRIC COMPANY (US) | 1981-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10364233-B2 | Piperidine derivative and methods of use thereof | PSEN1, PSEN2, APP | ALDH1A1 369/4885KDM4E 104/4885HSD17B10 4015/4885 |
| US-20110071291-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | ACHE, H1-2, H1-0 | ALDH1A1 238/4885KDM4E 1084/4885HSD17B10 1372/4885 |
| US-20180362505-A1 | Piperidine Derivative and Methods of Use Thereof | PSEN1, PSEN2, APP | ALDH1A1 369/4885KDM4E 104/4885HSD17B10 4015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.