SCHEMBL3365376

SCHEMBL3365376

CCOC(O)(O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
ALDH1A1 P00352 3/20 0.41
ALOX15 P16050 1/20 0.41
CYP2C19 P33261 3/20 0.40
KCNN4 O15554 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP3A4 P08684 1/20 0.39
SIGMAR1 Q99720 1/20 0.38
KIF11 P52732 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
HIF1A Q16665 1/20 0.38
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1802466 0.84 MAPK1 (0.46) ALDH1A1ALOX15CYP2C19KCNN4MAPK1
SCHEMBL11355373 0.82 ALDH1A1 (0.41) POLBALDH1A1ALOX15CYP2C19KCNN4
SCHEMBL1357103 0.80 ALDH1A1 (0.45) POLBALDH1A1ALOX15CYP2C19KCNN4
SCHEMBL10490529 0.79 LTA4H (0.44) ALDH1A1CYP2C19CYP1A2CYP2C9MAPK1
Fluorene SCHEMBL28835135 0.79 GABRP (0.40) POLBALDH1A1CYP1A2SMN1; SMN2CYP3A4
SCHEMBL27845934 0.78 KCNN4 (0.41) POLBALDH1A1ALOX15CYP2C19KCNN4
SCHEMBL27650370 0.78 MAPK1 (0.41) ALDH1A1ALOX15CYP2C19KCNN4MAPK1
SCHEMBL27691475 0.78 ALDH1A1 (0.39) POLBALDH1A1ALOX15CYP2C19KCNN4
SCHEMBL6631331 0.77 ALDH1A1 (0.41) POLBALDH1A1ALOX15CYP2C19KCNN4
SCHEMBL9194628 0.77 KCNN4 (0.40) ALDH1A1ALOX15KCNN4MAPK1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074887-A1 PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF Sea Pharmaceuticals LLC. (US) 2025-03-06 US claimed
WO-2021133774-A1 METHOD FOR DEPOSITING A FILM VERSUM MATERIALS US, LLC (US) 2021-07-01 WO claimed
CN-108779202-A CURABLE POLYFARNESENE-BASED COMPOSITIONS 飞纳技术有限公司 2018-11-09 CN claimed
US-20080045712-A1 Process for Preparing 4-Aminopyrimidine Compound UBE INDUSTRIES, LTD. (JP) 2008-02-21 US claimed
US-4268643-A ENDCAPPING BY ETHERIFICATION OR ESTERIFICATION SOCIETA ITALIANA RESINE S.I.R. S.P.A. (IT) 1981-05-19 US claimed
JP-57021403-A None JP disclosed
US-20250074887-A1 PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF Sea Pharmaceuticals LLC. (US) 2025-03-06 US disclosed
CN-119371772-A Polyacetal resin composition 旭化成株式会社 2025-01-28 CN disclosed
WO-2024204168-A1 CARBON NANOTUBE DISPERSION PASTE, COMPOSITE PASTE, AND LITHIUM ION SECONDARY BATTERY ELECTRODE LAYER PRODUCTION METHOD 関西ペイント株式会社 2024-10-03 WO disclosed
WO-2024204177-A1 METHOD FOR PRODUCING CARBON NANOTUBE DISPERSION PASTE AND METHOD FOR PRODUCING MIXTURE PASTE FOR LITHIUM-ION SECONDARY BATTERY 関西ペイント株式会社 2024-10-03 WO disclosed
CN-115197531-B Polyoxymethylene composition 旭化成株式会社 2024-10-01 CN disclosed
CN-118515949-A Polyacetal resin composition 旭化成株式会社 2024-08-20 CN disclosed
EP-0096770-A1 Process for producing olefin polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-12-28 EP disclosed
US-4421873-A FOUNDRY CORES AND MOLDS INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1983-12-20 US disclosed
US-4409378-A COORDINATION CATALYSTS OF METAL, ORTHOCARBOXYLIC ESTER COMPLEXES MITSUI TOATSU CHEMICALS, INC. (JP) 1983-10-11 US disclosed
US-4393152-A SUBSTITUTED PHENOL INTERNATIONAL MINERALS & CHEMICALS CORP. (US) 1983-07-12 US disclosed
US-4389498-A DIACETYLENE COMPOUND, FOUNDRIES INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1983-06-21 US disclosed
JP-S5721403-A POLYMERIZATION OF ALPHA-OLEFIN MITSUI TOATSU CHEM INC 1982-02-04 JP disclosed
US-4268643-A ENDCAPPING BY ETHERIFICATION OR ESTERIFICATION SOCIETA ITALIANA RESINE S.I.R. S.P.A. (IT) 1981-05-19 US disclosed
US-4220745-A STEREOSPECIFIC; ACTIVATED TITANIUM COORDINATION CATALYST MITSUI TOATSU CHEMICALS, INC. (JP) 1980-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074887-A1 PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF GABRQ, GRIK5, CYP3A7 POLB 4272/4885ALDH1A1 501/4885ALOX15 616/4885
US-20080045712-A1 Process for Preparing 4-Aminopyrimidine Compound ALKBH1, CBR1, CYP4B1 POLB 1418/4885ALDH1A1 279/4885ALOX15 1261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.