Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2272346 | 0.81 | KDM4E (0.41) | RAD51LOXL2KDM4EHSD17B10FGFR1 | |
| SCHEMBL2270590 | 0.77 | RAD51 (0.39) | RAD51LOXL2KDM4ECYP1A2NPC1 | |
| SCHEMBL2267039 | 0.76 | MEN1 (0.43) | LOXL2KDM4EHSD17B10CYP1A2PIK3CA | |
| SCHEMBL2267410 | 0.74 | HTT (0.48) | HSD17B10FGFR1 | |
| SCHEMBL828724 | 0.66 | NLRP3 (0.45) | NLRP3KDM4EHSD17B10TLR8ACSS2 | |
| SCHEMBL24553486 | 0.66 | ALDH1A1 (0.60) | NLRP3KDM4EHSD17B10ACSS2NQO2 | |
| SCHEMBL1104855 | 0.64 | RAB9A (0.59) | KDM4EHSD17B10ACSS2CYP1A2NPC1 | |
| SCHEMBL19714785 | 0.63 | HTR3E (0.41) | NLRP3KDM4EHSD17B10TLR8ACSS2 | |
| SCHEMBL4597356 | 0.63 | NLRP3 (0.42) | NLRP3KDM4EHSD17B10TLR8ACSS2 | |
| SCHEMBL10980166 | 0.63 | NLRP3 (0.42) | NLRP3KDM4EHSD17B10TLR8ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1070 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11555017-B2 | Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres | L'OREAL (FR) | 2023-01-17 | — | — | US | claimed |
| US-20220183940-A1 | DYEING PROCESS USING PEROXYGENATED SALTS AND A SUBSTRATE COMPRISING OXIDATION DYES | L'OREAL (FR) | 2022-06-16 | — | — | US | claimed |
| EP-3946217-A1 | DYEING PROCESS USING PEROXYGENATED SALTS AND A SUBSTRATE COMPRISING OXIDATION DYES | L'OREAL (FR) | 2022-02-09 | — | — | EP | claimed |
| CN-112089633-A | Oxidation dyeing method | 莱雅公司 | 2020-12-18 | — | — | CN | claimed |
| US-20200392088-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2020-12-17 | — | — | US | claimed |
| WO-2020201157-A1 | DYEING PROCESS USING PEROXYGENATED SALTS AND A SUBSTRATE COMPRISING OXIDATION DYES | L'OREAL (FR) | 2020-10-08 | — | — | WO | claimed |
| EP-3687978-A1 | PARA-PHENYLENEDIAMINE BASES WITH CATIONIC HETEROCYCLES, AND THE USE OF SAME FOR OXIDATION DYEING KERATIN FIBRES | L'Oreal (FR) | 2020-08-05 | — | — | EP | claimed |
| EP-3464247-B1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | OREAL (FR) | 2020-03-11 | — | — | EP | claimed |
| EP-3464247-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'Oréal (FR) | 2019-04-10 | — | — | EP | claimed |
| WO-2019063696-A1 | PARA-PHENYLENEDIAMINE BASES WITH CATIONIC HETEROCYCLES, AND THE USE OF SAME FOR OXIDATION DYEING KERATIN FIBRES | L' OREAL (FR) | 2019-04-04 | — | — | WO | claimed |
| EP-1047380-B1 | KERATINOUS FIBRE OXIDATION DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME | OREAL (FR) | 2004-05-06 | — | — | EP | claimed |
| US-6576024-B1 | Cosmetic mixture for the oxidation tinting of keratin fibres, containing in a support material suitable for tinting keratin fibres (a) at least one laccase- type enzyme; (b) at least one polymer thickener selected from polymers | L'OREAL S.A. (FR) | 2003-06-10 | — | — | US | claimed |
| EP-0891181-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-AZOLE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | OREAL (FR) | 2003-05-14 | — | — | EP | claimed |
| US-6537328-B1 | Hair dye | L'OREAL S.A. (FR) | 2003-03-25 | — | — | US | claimed |
| US-6471730-B1 | READY TO USE HAIR DYE CONTAINING OXIDATION COLORING AGENT, CATIONIC POLYMERS AND ENZYME; HYDROGEN PEROXIDE FREE; HOMOGENEOUS, INTENSE; NONDEGRADING OR DECOLOURING OF KERATINOUS FIBERS | L'OREAL (FR) | 2002-10-29 | — | — | US | claimed |
| US-20020007523-A1 | Compositions for dyeing keratinous fibres, containing pyrazolo-azoles; their use for dyeing, as couplers; method of dyeing | L' OREAL S.A. | 2002-01-24 | — | — | US | claimed |
| EP-1047379-B1 | COMPOSITION FOR THE OXIDATIVE DYEING OF KERATINIC FIBERS COMPRISING A LACCASE AND DEYING PROCESS USING SUCH A COMPOSITION | OREAL (FR) | 2001-10-10 | — | — | EP | claimed |
| EP-1047377-B1 | DYEING COMPOSITION CONTAINING A LACCASE AND KERATINOUS FIBRE DYEING METHODS USING SAME | OREAL (FR) | 2001-06-27 | — | — | EP | claimed |
| EP-1047376-B1 | KERATINOUS FIBRE DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME | OREAL (FR) | 2001-05-23 | — | — | EP | claimed |
| US-6231623-B1 | OXIDATIVE DYES | L'OREAL S.A. (FR) | 2001-05-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392088-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | KRT18, ALK, AOC1 | RAD51 2264/4885NLRP3 1692/4885LOXL2 1238/4885 |
| US-20220183940-A1 | DYEING PROCESS USING PEROXYGENATED SALTS AND A SUBSTRATE COMPRISING OXIDATION DYES | KRT18, PPOX, PRDX5 | RAD51 1562/4885NLRP3 3900/4885LOXL2 1265/4885 |
| US-20020007523-A1 | Compositions for dyeing keratinous fibres, containing pyrazolo-azoles; their use for dyeing, as couplers; method of dyeing | KRT18, ZYX, CBR3 | RAD51 1306/4885NLRP3 1068/4885LOXL2 3614/4885 |
| US-11555017-B2 | Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres | KRT18, ALK, AOC1 | RAD51 2254/4885NLRP3 1966/4885LOXL2 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.