Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.77 |
| ▸ | MAPT | P10636 | 11/20 | 0.77 |
| ▸ | MEN1 | O00255 | 10/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.62 |
| ▸ | BLM | P54132 | 4/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16705993 | 0.94 | MAPT (0.68) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL17466932 | 0.88 | MAPT (1.00) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL19469440 | 0.88 | KMT2A (0.59) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| Benzoic Acid SCHEMBL28633844 | 0.83 | ALDH1A1 (0.53) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL17466936 | 0.81 | MAPT (0.85) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL11957026 | 0.80 | GABRA1 (0.53) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL13908793 | 0.80 | GABRA1 (0.53) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL12755365 | 0.80 | GABRA1 (0.53) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL1238796 | 0.79 | MEN1 (1.00) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL21430771 | 0.78 | ALDH1A1 (0.46) | KMT2AMAPTMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372510-B | Preparation method of viscosity-reducing and mud-resisting polycarboxylate superplasticizer | 贵州鼎盛建材实业有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-113372510-A | Preparation method of viscosity-reducing and mud-resisting polycarboxylate superplasticizer | 贵州鼎盛建材实业有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-120247768-B | 2, 3-Disubstituted indole derivative and preparation method thereof | 齐鲁理工学院 | 2025-08-05 | — | — | CN | disclosed |
| CN-120247768-A | 2, 3-Disubstituted indole derivative and preparation method thereof | 齐鲁理工学院 | 2025-07-04 | — | — | CN | disclosed |
| CN-117551025-A | Preparation method of 4, 4-dicyano-2-alkyl-pyrrolidine-2-carboxylic ester derivative | 华北水利水电大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-116535368-A | Dicyanomethane compound and synthesis method and application thereof | 浙江理工大学嵊州创新研究院有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-114177942-B | Catalyst for condensation reaction of aldehyde and malononitrile Knoevenagel and preparation method thereof | 兰州大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-113058653-B | Catalyst for Knoevenagel condensation reaction of aldehyde and malononitrile and preparation method thereof | 兰州大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-113372510-B | Preparation method of viscosity-reducing and mud-resisting polycarboxylate superplasticizer | 贵州鼎盛建材实业有限公司 | 2022-08-19 | — | — | CN | disclosed |
| EP-3553097-B1 | COPOLYMER AND OPTICAL FILM USING SAME | TOSOH CORP (JP) | 2022-05-04 | — | — | EP | disclosed |
| US-20220096450-A1 | Compounds and Methods for Treating or Preventing Heart Failure | DREXEL UNIVERSITY | 2022-03-31 | — | — | US | disclosed |
| US-20030216382-A1 | Pyridine and pyrimidine derivatives | HOFFMAN-LA ROCHE INC. | 2003-11-20 | — | — | US | disclosed |
| WO-2003068757-A1 | NOVEL PYRIDIN- AND PYRIMIDIN-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-21 | — | — | WO | disclosed |
| EP-0357783-B1 | SECONDARY NON-LINEAR OPTICAL MATERIAL AND NON-LINEAR OPTICAL ELEMENT PREPARED THEREFROM | SUMITOMO ELECTRIC INDUSTRIES (JP) | 1994-10-26 | — | — | EP | disclosed |
| EP-0357783-A1 | SECONDARY NON-LINEAR OPTICAL MATERIAL AND NON-LINEAR OPTICAL ELEMENT PREPARED THEREFROM | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1990-03-14 | — | — | EP | disclosed |
| US-4719245-A | TRIMERIZATION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1988-01-12 | — | — | US | disclosed |
| US-4703099-A | CATALYTICALLY TRIMERIZING ISOCYANATES | THE DOW CHEMICAL COMPANY (US) | 1987-10-27 | — | — | US | disclosed |
| US-4632989-A | KETENE AMINAL-OLEFIN REACTION PRODUCT AS CATALYSTS | THE DOW CHEMICAL COMPANY (US) | 1986-12-30 | — | — | US | disclosed |
| US-4536490-A | REACTION PRODUCT OF KETENE-AMINAL AND UNSATURATED COMPOUND | THE UPJOHN COMPANY (US) | 1985-08-20 | — | — | US | disclosed |
| US-4184871-A | A,B-UNSATURATED NITRILE SENSITIZER | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1980-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220096450-A1 | Compounds and Methods for Treating or Preventing Heart Failure | SQOR, QSOX1, KEAP1 | KMT2A 677/4885MAPT 4525/4885MEN1 3644/4885 |
| US-20030216382-A1 | Pyridine and pyrimidine derivatives | DPP4, GPR119, G6PC1 | KMT2A 3893/4885MAPT 4559/4885MEN1 3734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.