Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Rhodamine 6G. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rhodamine 6G SCHEMBL4817749 | 0.98 | ABCB1 (0.38) | ABCB1USP2CFTRPAX8ATM | |
| Rhodamine 6G SCHEMBL10028465 | 0.98 | ABCB1 (0.38) | ABCB1USP2CFTRPAX8ATM | |
| Rhodamine 6G SCHEMBL1495836 | 0.98 | ABCB1 (0.38) | ABCB1USP2CFTRPAX8ATM | |
| Rhodamine 6G SCHEMBL5606069 | 0.97 | USP2 (0.38) | ABCB1USP2CFTRPAX8ATM | |
| Rhodamine 6G SCHEMBL5403477 | 0.97 | USP2 (0.38) | ABCB1USP2CFTRPAX8ATM | |
| Rhodamine 6G SCHEMBL23064835 | 0.97 | USP2 (0.38) | ABCB1USP2CFTRPAX8ATM | |
| Rhodamine 6G SCHEMBL15348373 | 0.97 | USP2 (0.38) | ABCB1USP2CFTRPAX8ATM | |
| Rhodamine 6G SCHEMBL23064834 | 0.97 | USP2 (0.38) | ABCB1USP2CFTRPAX8ATM | |
| Rhodamine 6G SCHEMBL58076 | 0.97 | USP2 (0.38) | ABCB1USP2CFTRPAX8ATM | |
| Rhodamine 6G SCHEMBL8647391 | 0.97 | USP2 (0.38) | ABCB1USP2CFTRPAX8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030108488-A1 | Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants | PROCTER & GAMBLE COMPANY, THE | 2003-06-12 | — | — | US | claimed |
| CN-122095314-A | Photosensitive resin laminate, method for forming resist pattern, and method for manufacturing wiring board having conductor pattern | — | 2026-05-26 | — | — | CN | disclosed |
| WO-2026100708-A1 | PHOTOSENSITIVE RESIN LAMINATE, PHOTOSENSITIVE ELEMENT, AND PATTERN FORMING METHOD | 旭化成株式会社 | 2026-05-15 | — | — | WO | disclosed |
| CN-122029490-A | Photosensitive resin laminate, method for forming resist pattern, and method for forming wiring board | 旭化成株式会社 | 2026-05-12 | — | — | CN | disclosed |
| CN-114114841-B | Photosensitive resin laminate and method for forming resist pattern | 旭化成株式会社 | 2026-05-12 | — | — | CN | disclosed |
| EP-4726016-A1 | ADDITIVE COMPOSITION FOR LUBRICANTS AND METHOD OF USE THEREOF | Syensqo Specialty Polymers Italy S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| US-20260098226-A1 | ADDITIVE COMPOSITION FOR LUBRICANTS AND METHOD OF USE THEREOF | Syensqo Specialty Polymers Italy S.p.A. (IT) | 2026-04-09 | — | — | US | disclosed |
| CN-121574722-A | Plasma as afterglow excitation source | 中国科学院深圳先进技术研究院 | 2026-02-27 | — | — | CN | disclosed |
| CN-120077329-A | Photosensitive resin composition, photosensitive resin laminate, and method for forming resist pattern | 旭化成株式会社 | 2025-05-30 | — | — | CN | disclosed |
| CN-120044756-A | Photosensitive resin composition | 旭化成株式会社 | 2025-05-27 | — | — | CN | disclosed |
| US-20030108488-A1 | Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants | PROCTER & GAMBLE COMPANY, THE | 2003-06-12 | — | — | US | disclosed |
| US-20020068293-A1 | Arrays having background features and methods for using the same | AGILENT TECHNOLOGIES, INC. | 2002-06-06 | — | — | US | disclosed |
| US-20020051973-A1 | TECHNIQUES FOR ASSESSING NONSPECIFIC BINDING OF NUCLEIC ACIDS TO SURFACES | AGILENT TECHNOLOGIES, INC. | 2002-05-02 | — | — | US | disclosed |
| US-6335531-B1 | Modification of resist and/or resist processing with fluorescence detection | MICRON TECHNOLOGY, INC. | 2002-01-01 | — | — | US | disclosed |
| US-5741662-A | Direct stain specific binding assays for microorganisms | QUIDEL CORPORATION (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1997022714-A1 | DIRECT STAIN SPECIFIC BINDING ASSAYS FOR MICROORGANISMS | QUIDEL CORPORATION (US) | 1997-06-26 | — | — | WO | disclosed |
| US-4824827-A | DYE, PROTON DONOR | S. C. JOHNSON & SON, INC. (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0309173-A2 | Time-color indicators | S.C. JOHNSON & SON, INC. (US) | 1989-03-29 | — | — | EP | disclosed |
| EP-0093337-B1 | PHOTOGRAPHIC REGISTRATION PROCESS | Agfa-Gevaert AG (DE) | 1985-12-04 | — | — | EP | disclosed |
| US-4543308-A | EXPOSURE AND DEVELOPMENT OF PHOTOSENSITIVE LAYER CONTAINING SILVER HALIDE EMULSION AND LUMINESCENCE COMPOUND, SCANNING AND ELECTRICSL | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1985-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108488-A1 | Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants | TAS2R10, TAS1R1, TAS2R40 | ABCB1 2085/4885USP2 4290/4885CFTR 1197/4885 |
| US-20260098226-A1 | ADDITIVE COMPOSITION FOR LUBRICANTS AND METHOD OF USE THEREOF | FGB, PF4, GFRA1 | ABCB1 435/4885USP2 4269/4885CFTR 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.