SCHEMBL3372289

SCHEMBL3372289

O=C(O)c1cnc2c(F)cccc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 5/20 0.65
MGAM O43451 1/20 0.56
COPS5 Q92905 4/20 0.48
STAMBP O95630 3/20 0.48
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
HPGDS O60760 1/20 0.43
EGLN1 Q9GZT9 1/20 0.43
TTR P02766 1/20 0.42
HCAR2 Q8TDS4 1/20 0.41
PARP1 P09874 2/20 0.40
PTPN1 P18031 1/20 0.40
SLC22A12 Q96S37 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.39
P4HA1 P13674 1/20 0.39
P4HTM Q9NXG6 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA6 P23280 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6084822 0.98 PSMD14 (0.63) PSMD14MGAMCOPS5STAMBPMEN1
SCHEMBL19346770 0.85 PSMD14 (0.66) PSMD14COPS5STAMBPHPGDSPARP1
SCHEMBL20821492 0.85 PSMD14 (0.48) PSMD14MGAMCOPS5STAMBPHPGDS
SCHEMBL29688144 0.85 PSMD14 (0.66) PSMD14COPS5STAMBPHPGDSPARP1
SCHEMBL2204711 0.81 PSMD14 (0.67) PSMD14MGAMCOPS5STAMBPMEN1
SCHEMBL10464539 0.81 PSMD14 (0.67) PSMD14MGAMCOPS5STAMBPMEN1
SCHEMBL15861797 0.81 PSMD14 (0.67) PSMD14MGAMCOPS5STAMBPMEN1
SCHEMBL17502526 0.81 PSMD14 (0.51) PSMD14MGAMCOPS5STAMBPMEN1
SCHEMBL30859346 0.80 CES2 (0.45) PSMD14COPS5STAMBPHPGDSPARP1
SCHEMBL27398957 0.80 CES2 (0.45) PSMD14COPS5STAMBPHPGDSPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117832755-A Functional diaphragm for lithium-sulfur battery and preparation method thereof 成都职业技术学院 2024-04-05 CN claimed
CN-1248968-A Heteroaryl-hexanoic acid amide derivatives, their preparation and their use as selective inhibitors of MIP-1-alpha binding to its CCRI receptor PFIZER (US) 2000-03-29 CN claimed
EP-0966443-A1 HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SELECTIVE INHIBITORS OF MIP-1-ALPHA BINDING TO ITS CCR1 RECEPTOR PFIZER INC. (US) 1999-12-29 EP claimed
WO-1998038167-A1 HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SELECTIVE INHIBITORS OF MIP-1-ALPHA BINDING TO ITS CCR1 RECEPTOR PFIZER INC. (US) 1998-09-03 WO claimed
US-20250171431-A1 HETEROCYCLIC INHIBITORS OF IGF-1R FOR TREATMENT OF DISEASE HORIZON THERAPEUTICS IRELAND DAC (IE) 2025-05-29 US disclosed
US-20250098677-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-03-27 US disclosed
WO-2025030163-A1 HETEROCYCLIC INHIBITORS OF IGF-1R FOR TREATMENT OF DISEASE HORIZON THERAPEUTICS IRELAND DAC (IE) 2025-02-06 WO disclosed
US-12201113-B2 Fungicidal compositions SYNGENTA CROP PROTECTION AG (CH) 2025-01-21 US disclosed
US-20240315247-A1 MICROBIOCIDAL QUINOLINE DIHYDRO-(THIAZINE)OXAZINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-09-26 US disclosed
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives SYNGENTA PARTICIPATIONS AG (CH) 2024-06-18 US disclosed
CN-117832755-A Functional diaphragm for lithium-sulfur battery and preparation method thereof 成都职业技术学院 2024-04-05 CN disclosed
WO-2024068656-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2024-04-04 WO disclosed
WO-2003000235-A1 PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUGS AND NEUTRAL POLYMERS PFIZER PRODUCTS INC. (US) 2003-01-03 WO disclosed
WO-2003000292-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING LOW-SOLUBILITY AND/OR ACID-SENSITIVE DRUGS AND NEUTRALIZED ACIDIC POLYMERS PFIZER PRODUCTS INC. (US) 2003-01-03 WO disclosed
WO-2003000294-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING A SOLID DISPERSION OF A POORLY-SOLUBLE DRUG IN A MATRIX AND A SOLUBILITY-ENHANCING POLYMER PFIZER PRODUCTS INC. (US) 2003-01-03 WO disclosed
WO-2003000238-A1 PHARMACEUTICAL COMPOSITIONS OF ADSORBATES OF AMORPHOUS DRUG PFIZER PRODUCTS INC. (US) 2003-01-03 WO disclosed
EP-1269994-A2 Pharmaceutical compositions comprising drug and concentration-enhancing polymers Pfizer Products Inc. (US) 2003-01-02 EP disclosed
US-20020198207-A1 Novel Hexanoic acid derivatives KATH JOHN CHARLES (US) 2002-12-26 US disclosed
US-6403587-B1 AUTOIMMUNE DISEASES, ACUTE AND CHRONIC INFLAMMATORY CONDITIONS, ALLERGIC CONDITIONS, INFECTION ASSOCIATED WITH INFLAMMATION, VIRAL, TRANSPLANTATION TISSUE REJECTION, ATHEROSCLEROSIS, RESTENOSIS, HIV INFECTIVITY, AND PFIZER INC. 2002-06-11 US disclosed
CN-1248968-A Heteroaryl-hexanoic acid amide derivatives, their preparation and their use as selective inhibitors of MIP-1-alpha binding to its CCRI receptor PFIZER (US) 2000-03-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12201113-B2 Fungicidal compositions CYP51A1, CYP4X1, CYP1B1 PSMD14 3354/4885MGAM 29/4885COPS5 2189/4885
US-12012399-B2 Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives TLR1, TLR5, IDO1 PSMD14 2489/4885MGAM 230/4885COPS5 2387/4885
US-20250098677-A1 FUNGICIDAL COMPOSITIONS CYP51A1, CYP4X1, CYP1B1 PSMD14 3354/4885MGAM 29/4885COPS5 2189/4885
US-20020198207-A1 Novel Hexanoic acid derivatives HCAR3, HCAR1, FFAR1 PSMD14 3557/4885MGAM 1794/4885COPS5 2188/4885
US-20240315247-A1 MICROBIOCIDAL QUINOLINE DIHYDRO-(THIAZINE)OXAZINE DERIVATIVES IFNG, TLR1, NOX1 PSMD14 3685/4885MGAM 1272/4885COPS5 3709/4885
US-20250171431-A1 HETEROCYCLIC INHIBITORS OF IGF-1R FOR TREATMENT OF DISEASE IGF1R, TRHR, TSHR PSMD14 3921/4885MGAM 3011/4885COPS5 2775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.