Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 12/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3448235 | 0.93 | SYK (0.49) | SYKAURKAMAPTNPSR1 | |
| SCHEMBL3374661 | 0.91 | SYK (0.45) | SYKPAK1CSNK2A1MAPTNPSR1 | |
| SCHEMBL3372082 | 0.91 | XDH (0.40) | SYKAURKACSNK2A1 | |
| SCHEMBL3450657 | 0.91 | SYK (0.39) | SYKAURKAMAPTNPSR1 | |
| SCHEMBL3452624 | 0.89 | SYK (0.48) | SYK | |
| SCHEMBL3450416 | 0.89 | GPR52 (0.42) | SYK | |
| SCHEMBL3450388 | 0.88 | MAPT (0.43) | SYKMAPTNPSR1 | |
| SCHEMBL3448606 | 0.88 | SYK (0.37) | SYKPAK1MAPTNPSR1 | |
| SCHEMBL3375503 | 0.88 | SYK (0.40) | SYKCSNK2A1MAPTNPSR1 | |
| SCHEMBL3374147 | 0.87 | SYK (0.37) | SYKMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820148-B2 | Use of a complex nutritional base in cosmetics, in particular for the hair | Thorel, Jean-Noël (FR) | 2010-10-26 | — | — | US | disclosed |
| US-20100137313-A1 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB | 2010-06-03 | — | — | US | disclosed |
| US-20100137313-A1 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB | 2010-06-03 | — | — | US | disclosed |
| US-20100137313-A1 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB | 2010-06-03 | — | — | US | disclosed |
| WO-2010038081-A2 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010038081-A2 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2010-04-08 | — | — | WO | disclosed |
| US-20070248559-A1 | Use of a complex nutritional base in cosmetics, in particular for the hair | JEAN-NOEL THOREL (FR) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137313-A1 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | SDHA, SDHB, UROD | SYK 804/4885AURKA 3990/4885PAK1 2792/4885 |
| US-20070248559-A1 | Use of a complex nutritional base in cosmetics, in particular for the hair | FGF1, S100B, SLC7A1 | SYK 4835/4885AURKA 3266/4885PAK1 1680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.