SCHEMBL337697

SCHEMBL337697

C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(OP(=O)(Oc3ccccc3)Oc3ccccc3)[C@H](C)[C@H]12

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PLCG1 P19174 1/20 0.42
ELANE P08246 7/20 0.41
RAB9A P51151 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
HTR2A P28223 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1198655 1.00 PLCG1 (0.42) PLCG1ELANERAB9ATDP1HTR2A
SCHEMBL14153496 1.00 PLCG1 (0.42) PLCG1ELANERAB9ATDP1HTR2A
SCHEMBL10013148 1.00 PLCG1 (0.42) PLCG1ELANERAB9ATDP1HTR2A
SCHEMBL407970 1.00 PLCG1 (0.42) PLCG1ELANERAB9ATDP1HTR2A
SCHEMBL8695596 1.00 PLCG1 (0.42) PLCG1ELANERAB9ATDP1HTR2A
SCHEMBL8924773 1.00 PLCG1 (0.42) PLCG1ELANERAB9ATDP1HTR2A
SCHEMBL13483984 1.00 PLCG1 (0.42) PLCG1ELANERAB9ATDP1HTR2A
SCHEMBL437737 1.00 PLCG1 (0.42) PLCG1ELANERAB9ATDP1HTR2A
SCHEMBL18977837 0.94 PLCG1 (0.40) PLCG1ELANERAB9AHTT
SCHEMBL10013149 0.94 PLCG1 (0.42) PLCG1ELANERAB9ATDP1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118604173-A Method for detecting genotoxic impurities in biapenem 北京悦康科创医药科技股份有限公司 2024-09-06 CN claimed
EP-4724107-A2 OPHTHALMIC FILMS Fount Bio, Inc. (US) 2026-04-15 EP disclosed
US-12398161-B2 Continuous preparation method for penem intermediate map Jilin Asymchem Pharmaceuticals Co., Ltd. (CN) 2025-08-26 US disclosed
EP-3978505-B1 METHOD FOR CONTINUOUSLY PREPARING MAP PENEM INTERMEDIATE JILIN ASYMCHEM PHARMACEUTICALS CO LTD (CN) 2025-07-30 EP disclosed
WO-2024254278-A9 OPHTHALMIC FILMS FOUNT BIO, INC. (US) 2025-02-13 WO disclosed
WO-2024254278-A2 OPHTHALMIC FILMS FOUNT BIO, INC. (US) 2024-12-12 WO disclosed
US-12084445-B2 Broad-spectrum carbapenems VenatoRx Pharmaceuticals, Inc. (US) 2024-09-10 US disclosed
CN-118604173-A Method for detecting genotoxic impurities in biapenem 北京悦康科创医药科技股份有限公司 2024-09-06 CN disclosed
CN-113710225-B Delivery and retention of active agents within the skin 范德生物公司 2024-06-21 CN disclosed
US-20230127944-A1 BROAD-SPECTRUM CARBAPENEMS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-04-27 US disclosed
US-20090299057-A1 MEROPENEM INTERMEDIATE IN NOVEL CRYSTALLINE FORM AND A METHOD OF MANUFACTURE OF MEROPENEM KHEMKA ASHWIN A 2009-12-03 US disclosed
US-20090143574-A1 Carbapenem Compound NIPPON SODA CO., LTD. (JP) 2009-06-04 US disclosed
US-7538212-B2 Intermediate for carbapenem compound for oral administration and process for producing the same KANEKA CORPORATION (JP) 2009-05-26 US disclosed
US-20090118496-A1 Crystallization Method for Intermediates of Carbapenem Antibiotics KANEKA CORPORATION (JP) 2009-05-07 US disclosed
US-20090118496-A1 Crystallization Method for Intermediates of Carbapenem Antibiotics KANEKA CORPORATION (JP) 2009-05-07 US disclosed
US-7524952-B2 Process for producing carbapenem compound for oral administration KANEKA CORPORATION (JP) 2009-04-28 US disclosed
EP-2006290-A1 IMPROVED PROCESS FOR PRODUCING CARBAPENEM COMPOUND Kaneka Corporation (JP) 2008-12-24 EP disclosed
EP-1956027-A1 CARBAPENEM COMPOUND NIPPON SODA CO., LTD. (JP) 2008-08-13 EP disclosed
US-20070197781-A1 PROCESSES FOR THE PREPARATION OF CARBAPENEMS RANBAXY LABORATORIES LIMITED (IN) 2007-08-23 US disclosed
WO-1996026939-A1 CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-09-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12398161-B2 Continuous preparation method for penem intermediate map PGM2, POLM, POR PLCG1 1364/4885ELANE 3800/4885RAB9A 2501/4885
US-20090299057-A1 MEROPENEM INTERMEDIATE IN NOVEL CRYSTALLINE FORM AND A METHOD OF MANUFACTURE OF MEROPENEM NT5C3B, CYP4B1, GNE PLCG1 1999/4885ELANE 3687/4885RAB9A 2703/4885
US-20090118496-A1 Crystallization Method for Intermediates of Carbapenem Antibiotics OTUB1, PYCARD, OTUD7B PLCG1 3317/4885ELANE 3442/4885RAB9A 3963/4885
US-20090143574-A1 Carbapenem Compound MGAM, SI, PDS5A PLCG1 3321/4885ELANE 2247/4885RAB9A 2019/4885
US-20230127944-A1 BROAD-SPECTRUM CARBAPENEMS MGAM, ALPI, SI PLCG1 1243/4885ELANE 690/4885RAB9A 1009/4885
US-20070197781-A1 PROCESSES FOR THE PREPARATION OF CARBAPENEMS MGAM, SI, TREH PLCG1 1770/4885ELANE 2492/4885RAB9A 2331/4885
US-12084445-B2 Broad-spectrum carbapenems MGAM, ALPI, SI PLCG1 1243/4885ELANE 690/4885RAB9A 1009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.