SCHEMBL3379652

SCHEMBL3379652

CC1=C(C)C(C)(C)C([Ti]Oc2c(-c3ccccc3)cccc2C(C)C)=C1C

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5709976 0.87 FAAH (0.32)
Hydrochloric Acid SCHEMBL394797 0.86 SCN5A (0.32)
Hydrochloric Acid SCHEMBL3625539 0.77 MAPK1 (0.36) ADRA2AADRA2BADRA2C
SCHEMBL3377120 0.76 ADRA2A (0.31) ADRA2AADRA2BADRA2C
SCHEMBL618897 0.74
Hydrochloric Acid SCHEMBL392239 0.71 LMNA (0.31)
SCHEMBL3843229 0.69 PTPN5 (0.35)
SCHEMBL617346 0.69 PDE4B (0.43) ADRA2AADRA2BADRA2C
Hydrochloric Acid SCHEMBL715703 0.67 GABRA1 (0.33)
Biphenyl SCHEMBL821668 0.66 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2324067-B1 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SABIC SK NEXLENE COMPANY PTE LTD (SG) 2018-04-25 EP disclosed
US-20100120981-A1 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SABIC SK NEXLENE COMPANY PTE. LTD. (SG) 2010-05-13 US disclosed
WO-2010030145-A2 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SK ENERGY CO., LTD. (KR) 2010-03-18 WO disclosed