Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 6/20 | 0.34 |
| ▸ | ADRA2B known ✓ | P18089 | 6/20 | 0.34 |
| ▸ | ADRA2C known ✓ | P18825 | 6/20 | 0.34 |
| ▸ | MAOA known ✓ | P21397 | 3/20 | 0.34 |
| ▸ | MAOB known ✓ | P27338 | 3/20 | 0.34 |
| ▸ | HTR7 known ✓ | P34969 | 1/20 | 0.34 |
| ▸ | ADRB2 known ✓ | P07550 | 3/20 | 0.33 |
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.31 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | FABP7 | O15540 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377120 | 0.93 | ADRA2A (0.31) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| Hydrochloric Acid SCHEMBL3615426 | 0.82 | MEN1 (0.33) | RAB9ANISCHALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL461532 | 0.77 | NISCH (0.32) | NISCHTDP1KDM4EALDH1A1 | |
| SCHEMBL3379652 | 0.77 | ADRA2A (0.33) | ADRA2AADRA2BADRA2C | |
| SCHEMBL3700605 | 0.75 | MAPT (0.38) | NISCHLMNATDP1KDM4E | |
| Biphenyl SCHEMBL821668 | 0.71 | ALDH1A1 (0.36) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL392239 | 0.71 | LMNA (0.31) | LMNA | |
| SCHEMBL3611287 | 0.70 | HTR7 (0.35) | MAPK1TP53RAB9AHTR7ADRB2 | |
| SCHEMBL370497 | 0.70 | HTR7 (0.35) | MAPK1TP53RAB9AHTR7ADRB2 | |
| Hydrochloric Acid SCHEMBL346593 | 0.69 | ADRA2A (0.34) | MAPK1TP53RAB9AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117920354-A | Catalyst for synthesizing alpha-olefin by oligomerization of ethylene and preparation method thereof | 朴烯晶新能源材料(上海)有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-116178604-B | Preparation method of thermoplastic polyolefin elastomer with high volume resistivity | 海南贝欧亿科技有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117089006-A | Preparation method of bio-based thermoplastic polyolefin elastomer | 海南贝欧亿科技有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-117050221-A | Ultraviolet aging resistant thermoplastic polyolefin elastomer and preparation method thereof | 海南贝欧亿科技有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-115746188-B | Preparation method of color-controllable thermoplastic polyolefin elastomer | 山东京博石油化工有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116173882-A | Apparatus and method for producing polyolefin elastomer | 国家能源集团宁夏煤业有限责任公司 | 2023-05-30 | — | — | CN | claimed |
| CN-116178604-A | Preparation method of thermoplastic polyolefin elastomer with high volume resistivity | 山东京博石油化工有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-115926076-A | Production method and device of polypropylene alloy | 北京鑫美格工程设计有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115894157-A | Method for pretreating raw materials in polyolefin polymerization process | 山东京博石油化工有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115850586-A | Comb-shaped ethylene-propylene copolymer, cross-linked comb-shaped ethylene-propylene copolymer and preparation method thereof | 浙江大学 | 2023-03-28 | — | — | CN | claimed |
| CN-113896998-A | Preparation method of polyolefin thermoplastic elastomer based on dynamic crosslinking modification | 浙江大学 | 2022-01-07 | — | — | CN | claimed |
| CN-110092856-B | Liquid copolymerized olefin, preparation method and application | 香港中文大学（深圳） | 2021-10-22 | — | — | CN | claimed |
| CN-111732682-A | Preparation method of cross-linked polyolefin for packaging high-light-transmittance solar cell | 浙江大学 | 2020-10-02 | — | — | CN | claimed |
| CN-111704703-A | Preparation method of crosslinkable comb-shaped vinyl olefin polymer | 浙江大学 | 2020-09-25 | — | — | CN | claimed |
| CN-111690086-A | Preparation method of rapid crosslinking type propenyl polyolefin for packaging solar cell | 浙江大学衢州研究院 | 2020-09-22 | — | — | CN | claimed |
| CN-111662417-A | Preparation method of novel crosslinkable comb-shaped propenyl olefin polymer | 浙江大学衢州研究院 | 2020-09-15 | — | — | CN | claimed |
| CN-111635494-A | Preparation method of comb-shaped propenyl olefin polymer | 浙江大学衢州研究院 | 2020-09-08 | — | — | CN | claimed |
| CN-109384885-B | Preparation method of comb-shaped vinyl polyolefin thermoplastic elastomer | 浙江大学 | 2020-08-11 | — | — | CN | claimed |
| CN-109535323-B | Preparation method of comb-shaped propenyl polyolefin thermoplastic elastomer | 浙江大学 | 2020-08-11 | — | — | CN | claimed |
| CN-109456445-B | Preparation method of comb-shaped propenyl polyolefin thermoplastic elastomer | 浙江大学 | 2020-08-04 | — | — | CN | claimed |