Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11740225 | 0.84 | ALDH1A1 (0.51) | ALDH1A1GAATHRBMAPTACP3 | |
| SCHEMBL28493005 | 0.84 | MAPT (0.49) | ALDH1A1TDP1CYP3A4ALOX15GAA | |
| SCHEMBL14744361 | 0.83 | ALDH1A1 (0.44) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL6556910 | 0.83 | LMNA (0.50) | ALDH1A1CYP3A4GAAMEN1KMT2A | |
| SCHEMBL8744236 | 0.81 | CRHBP (0.52) | ALDH1A1TDP1CYP3A4MEN1KMT2A | |
| SCHEMBL10924875 | 0.81 | PDE7A (0.47) | ALDH1A1TDP1CYP3A4ALOX15GAA | |
| SCHEMBL14744514 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL1813716 | 0.78 | CA12 (0.58) | ALDH1A1TDP1THRBMEN1KMT2A | |
| SCHEMBL6244176 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TDP1CYP3A4ALOX15GAA | |
| SCHEMBL9414517 | 0.77 | ACP3 (0.62) | ALDH1A1ALOX15MEN1KMT2AACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160304-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-1844768-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160304-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | NR3C2, AGTR1, AGTR2 | ALDH1A1 1053/4885TDP1 4661/4885CYP3A4 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.