SCHEMBL338126

SCHEMBL338126

O=C(Cl)c1ccc(C(=O)Cl)c2c(C(=O)Cl)ccc(C(=O)Cl)c12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.53
ALDH1A1 P00352 8/20 0.46
ALOX15 P16050 2/20 0.46
TSHR P16473 2/20 0.33
KDM4E B2RXH2 2/20 0.33
CASP1 P29466 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33
MAOB P27338 1/20 0.32
CES2 O00748 3/20 0.32
CES1 P23141 2/20 0.32
SELL P14151 1/20 0.31
SELP P16109 1/20 0.31
KMT2A Q03164 2/20 0.30
MEN1 O00255 1/20 0.30
HSD17B10 Q99714 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
ATM Q13315 1/20 0.30
GFER P55789 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28927985 0.81 ALDH1A1 (0.41) CYP1A2ALDH1A1ALOX15TSHRKDM4E
SCHEMBL604621 0.79 ALDH1A1 (0.41) CYP1A2ALDH1A1ALOX15TSHRKDM4E
SCHEMBL8904804 0.78 ALDH1A1 (0.48) CYP1A2ALDH1A1ALOX15TSHRKDM4E
SCHEMBL103521 0.78 ALDH1A1 (0.44) CYP1A2ALDH1A1ALOX15TSHRKDM4E
SCHEMBL5298121 0.78 SELL (0.46) CYP1A2ALDH1A1ALOX15TSHRKDM4E
SCHEMBL11211669 0.75 ALDH1A1 (0.42) CYP1A2ALDH1A1ALOX15TSHRKDM4E
SCHEMBL29868398 0.75 HSD17B10 (0.50) CYP1A2ALDH1A1ALOX15TSHRKDM4E
SCHEMBL1791928 0.75 HSD17B10 (0.50) CYP1A2ALDH1A1ALOX15TSHRKDM4E
SCHEMBL422 0.73 ALDH1A1 (0.67) ALDH1A1ALOX15TSHRKDM4ESMN1; SMN2
SCHEMBL4607896 0.73 HSD17B10 (0.48) CYP1A2ALDH1A1ALOX15TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 819 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0229470-B1 BRANCHED COPOLYETHERKETONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-30 EP claimed
US-4720537-A Branched copolyetherketones E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-19 US claimed
EP-0229470-A1 Branched copolyetherketones E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-07-22 EP claimed
US-4582893-A Aromatic polyesters which contain terminal or lateral radicals with two conjugated double bonds BAYER AKTIENGESELLSCHAFT (DE) 1986-04-15 US claimed
US-20260117062-A1 MINERAL-FILLED POLYCARBONATE AND/OR POLYESTER CARBONATE MOLDING COMPOUND WITH A GOOD DEGREE OF THERMAL STABILITY COVESTRO DEUTSCHLAND AG (DE) 2026-04-30 US disclosed
US-12573701-B2 Modular battery pack COVESTRO LLC (US) 2026-03-10 US disclosed
US-12552904-B2 Polyphosphazene and molding compound containing the polyphosphazene COVESTRO DEUTSCHLAND AG (DE) 2026-02-17 US disclosed
US-20260002024-A1 FLAME RETARDANT POLYCARBONATE FORMULATIONS TRINSEO EUROPE GMBH (CH) 2026-01-01 US disclosed
EP-4430122-B1 HEAT-RESISTANT THERMOPLASTIC ELECTROSTATIC DISSIPATIVE COMPOSITION COVESTRO DEUTSCHLAND AG (DE) 2025-12-03 EP disclosed
EP-4646459-A1 MINERAL-FILLED POLYCARBONATE AND/OR POLYESTER CARBONATE MOLDING COMPOUND WITH A GOOD DEGREE OF THERMAL STABILITY Covestro Deutschland AG (DE) 2025-11-12 EP disclosed
US-12466168-B2 Multi-layer composite article including a cover layer and a PC/ABS layer and methods thereof TRINSEO EUROPE GMBH (CH) 2025-11-11 US disclosed
US-12466949-B2 E/E component containing polycarbonate material having high tracking resistance COVESTRO DEUTSCHLAND AG (DE) 2025-11-11 US disclosed
US-4714746-A Process for the preparation of aromatic polyester-carbonates having improved notched impact strength, and polyester-carbonates prepared thereby and their use for the production of mouldings, films and coatings BAYER AKTIENGESELLSCHAFT (DE) 1987-12-22 US disclosed
US-4704430-A BLENDS OF POLYCARBONATES, POLYESTERS AND BLOCK POLYCARBONATE ETHER COPOLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1987-11-03 US disclosed
EP-0229470-A1 Branched copolyetherketones E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-07-22 EP disclosed
US-4645806-A MOLDING MATERIALS, ENGINEERING THERMOPLASTICS BAYER AKTIENGESELLSCHAFT (DE) 1987-02-24 US disclosed
US-4582893-A Aromatic polyesters which contain terminal or lateral radicals with two conjugated double bonds BAYER AKTIENGESELLSCHAFT (DE) 1986-04-15 US disclosed
US-4388246-A THERMAL SPLITTING OF CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed
US-4366276-A Flame-resistant moulding materials based on thermoplastic aromatic polyesters and polyesters carbonates, a process for their production and their use in the production of moulded bodies BAYER AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed
US-4334053-A CHAIN TERMINATED BY ALKYL-SUBSTITUTED PHENOL, PHENYL HALOGORMATES OR PHENYLACYL CHLORIDES BAYER AKTIENGESELLSCHAFT (DE) 1982-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12573701-B2 Modular battery pack L1CAM, ITGB1, ITGB2 CYP1A2 4039/4885ALDH1A1 1316/4885ALOX15 3282/4885
US-12552904-B2 Polyphosphazene and molding compound containing the polyphosphazene PHOSPHO1, CCNE1, CCNE2 CYP1A2 789/4885ALDH1A1 2896/4885ALOX15 1276/4885
US-20260117062-A1 MINERAL-FILLED POLYCARBONATE AND/OR POLYESTER CARBONATE MOLDING COMPOUND WITH A GOOD DEGREE OF THERMAL STABILITY RCC1, HSD17B12, SMC4 CYP1A2 936/4885ALDH1A1 1445/4885ALOX15 340/4885
US-20260002024-A1 FLAME RETARDANT POLYCARBONATE FORMULATIONS PFAS, FGFR3, FGFR2 CYP1A2 3340/4885ALDH1A1 3626/4885ALOX15 726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.