Dimethylaminoethanol

Dimethylaminoethanol

SCHEMBL3381335

CN(C)CCO.NCCCO

nearest known ligand 0.63

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.63
TDP1 Q9NUW8 3/20 0.50
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
CHRM2 P08172 1/20 0.40
ALDH1A1 P00352 5/20 0.36
TSHR P16473 2/20 0.36
HRH4 Q9H3N8 2/20 0.32
CYP1A2 P05177 1/20 0.32
HRH2 P25021 1/20 0.32
HSD17B10 Q99714 1/20 0.31
DNM1 Q05193 1/20 0.31
CA12 O43570 1/20 0.30
CA2 P00918 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylaminoethanol SCHEMBL10935556 0.95 MAPT (0.57) MAPTTDP1CYP2C9CYP2C19CHRM2
SCHEMBL29132828 0.92 TDP1 (0.52) MAPTTDP1CYP2C9CYP2C19CHRM2
Dimethylaminoethanol SCHEMBL20677258 0.86 MAPT (0.75) MAPTTDP1CYP2C9CYP2C19CHRM2
Dimethylaminoethanol SCHEMBL28282228 0.86 MAPT (0.75) MAPTTDP1CYP2C9CYP2C19CHRM2
Dimethylaminoethanol SCHEMBL28288674 0.85 MAPT (0.57) MAPTTDP1CYP2C9CYP2C19CHRM2
SCHEMBL29132833 0.84 TDP1 (0.50) MAPTTDP1CYP2C9CYP2C19CHRM2
Trimethylammonium SCHEMBL27588412 0.83
Trimethylammonium SCHEMBL27700635 0.80 ALDH1A1 (0.41) MAPTTDP1CHRM2ALDH1A1TSHR
Trimethylammonium SCHEMBL27339214 0.80 ALDH1A1 (0.41) MAPTTDP1CHRM2ALDH1A1TSHR
Trimethylammonium SCHEMBL27700634 0.80 ALDH1A1 (0.41) MAPTTDP1CHRM2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670988-B1 ADDITIVE FOR REDUCING PAPER LINTING AND DUSTING BASF SE (DE) 2010-11-17 EP disclosed
US-7618697-B2 Coatings, films; environmentally friendly CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-11-17 US disclosed
US-7491294-B2 Compositions for reducing paper linting and dusting CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-02-17 US disclosed
US-20080319089-A1 Method of colouring carrier materials MULLER MARTIN 2008-12-25 US disclosed
US-20070128151-A1 Coatings, films; environmentally friendly CIBA SPECIALTY CHEMICALS CORP. 2007-06-07 US disclosed
US-20070051275-A1 Method of colouring carrier materials CIBA SPECIALTY CHEMICALS CORP. 2007-03-08 US disclosed
US-7077898-B2 Mixture of carbon black and sulfonate compound; for high molecular weight plastics, inks, automobile coating CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-07-18 US disclosed
EP-1670988-A1 ADDITIVE FOR REDUCING PAPER LINTING AND DUSTING Ciba SC Holding AG (CH) 2006-06-21 EP disclosed
EP-1587879-A1 SYNTHESIS OF SMALL PARTICLE SIZE QUINACRIDONE OF BETA CRYSTAL PHASE Ciba SC Holding AG (CH) 2005-10-26 EP disclosed
US-20050155162-A1 Process for the coloration of aluminium CIBA SPECIALTY CHEMICALS CORP. 2005-07-21 US disclosed
EP-1549714-A2 METHOD OF COLOURING CARRIER MATERIALS Ciba SC Holding AG (CH) 2005-07-06 EP disclosed
WO-2005038133-A1 ADDITIVE FOR REDUCING PAPER LINTING AND DUSTING CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-04-28 WO disclosed
US-20050077022-A1 Compositions for reducing paper linting and dusting CIBA SPECIALTY CHEMICALS CORP. 2005-04-14 US disclosed
WO-2005014727-A1 BLACK PIGMENT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-02-17 WO disclosed
US-20050014863-A1 Black pigment compositions PIGMENTS SERVICES, INC. 2005-01-20 US disclosed
WO-2004067642-A1 SYNTHESIS OF SMALL PARTICLE SIZE QUINACRIDONE OF BETA CRYSTAL PHASE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-12 WO disclosed
US-20040138436-A1 Water-soluble salt of sulfonamides as colorants for the pigmenting of porous materials and for use in inkjet printing SCHACHT HANS-THOMAS (DE) 2004-07-15 US disclosed
WO-2004033563-A2 METHOD OF COLOURING CARRIER MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-04-22 WO disclosed
EP-0754565-B1 A concentrated dampening solution with an improved anti-staining activity for printing with a lithographic printing plate obtained according to the silver salt diffusion transfer process AGFA GEVAERT NV (BE) 1999-06-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070128151-A1 Coatings, films; environmentally friendly CUTA, GAP43, NAPA MAPT 1308/4885TDP1 1022/4885CYP2C9 840/4885
US-20040138436-A1 Water-soluble salt of sulfonamides as colorants for the pigmenting of porous materials and for use in inkjet printing SULT1A1, SULT2A1, ATP1B2 MAPT 429/4885TDP1 3439/4885CYP2C9 1186/4885
US-20080319089-A1 Method of colouring carrier materials CRYAA, SLC67A1, SOD3 MAPT 1162/4885TDP1 2864/4885CYP2C9 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.