Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17294439 | 0.73 | THRA (0.35) | THRATHRB | |
| SCHEMBL6399457 | 0.73 | SOAT1 (0.37) | PTPN11MAPK8THRATHRBMAPT | |
| SCHEMBL15203963 | 0.72 | KDM4E (0.52) | PTPN11CYP2C9LMNAMEN1NR1I2 | |
| SCHEMBL30122764 | 0.71 | CNR2 (0.35) | PTPN11CNR2THRATHRBLMNA | |
| SCHEMBL627672 | 0.69 | CYP1A2 (0.39) | CNR2CNR1CYP2C9LMNAMEN1 | |
| SCHEMBL9993602 | 0.69 | SOAT1 (0.48) | MAPK8THRATHRBTSHR | |
| SCHEMBL8520508 | 0.69 | SOAT1 (0.48) | MAPK8THRATHRBTSHR | |
| Diethylene Glycol Monoethyl Ether SCHEMBL6065116 | 0.67 | THRB (0.34) | PTPN11THRATHRBLMNAMEN1 | |
| SCHEMBL3382019 | 0.67 | LTB4R (0.37) | PTPN11MAPK8 | |
| SCHEMBL2709504 | 0.67 | CYP1A2 (0.41) | CYP3A4MAPTTSHRALDH1A1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380288-B1 | Cosmetic and dermatological photoprotective compositions containing hydrophobic acrylamidomethylpropanesulphonic acid (AMPS) polymer | CLARIANT INTERNAT AG (CH) | 2010-11-17 | — | — | EP | disclosed |