Obovatal

Obovatal

SCHEMBL3383286

C=CCc1ccc(Oc2cc(/C=C/C=O)cc(O)c2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 1.00
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
XDH P47989 3/20 0.41
TNKS O95271 2/20 0.41
PARP1 P09874 1/20 0.41
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 2/20 0.39
ALOX5 P09917 1/20 0.39
AR P10275 1/20 0.39
PTGS1 P23219 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
TP53 P04637 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
POLB P06746 2/20 0.38
MAOA P21397 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14678673 0.90 MMP2 (0.82) MMP2ESR1ESR2XDHTNKS
Obovator SCHEMBL33525039 0.81 MMP2 (0.67) MMP2ESR1ESR2XDHTNKS
Obovator SCHEMBL454929 0.81 MMP2 (0.67) MMP2ESR1ESR2XDHTNKS
SCHEMBL565507 0.73 MMP2 (0.55) MMP2ESR1ESR2XDHALDH1A1
SCHEMBL565508 0.73 MMP2 (0.55) MMP2ESR1ESR2XDHALDH1A1
Isomagnolol SCHEMBL30069180 0.72 ALDH1A1 (0.66) MMP2XDHTNKSPARP1ALDH1A1
SCHEMBL18838060 0.70 TNKS (0.61) MMP2ESR1ESR2TNKSALDH1A1
SCHEMBL30114989 0.70 TNKS (0.69) MMP2ESR1ESR2XDHTNKS
SCHEMBL31046737 0.69 GABRA1 (0.66) MMP2ESR1ESR2XDHTNKS
SCHEMBL30284517 0.69 GABRA1 (0.66) MMP2ESR1ESR2XDHTNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367736-B2 Anticancer composition comprising obovatol or obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2013-02-05 US claimed
US-20080312337-A1 Anticancer Composition Comprising Obovatol or Obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2008-12-18 US claimed
US-20070037889-A1 Anticancer composition comprising obovatol or obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2007-02-15 US claimed
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA LLC (US) 2026-04-16 US disclosed
EP-4593859-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION Eresina, LLC (US) 2025-08-06 EP disclosed
WO-2024073013-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA, LLC (US) 2024-04-04 WO disclosed
WO-2024073011-A1 TOPICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA, LLC (US) 2024-04-04 WO disclosed
US-8367736-B2 Anticancer composition comprising obovatol or obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2013-02-05 US disclosed
US-8367736-B2 Anticancer composition comprising obovatol or obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2013-02-05 US disclosed
US-8367736-B2 Anticancer composition comprising obovatol or obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2013-02-05 US disclosed
US-8367736-B2 Anticancer composition comprising obovatol or obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2013-02-05 US disclosed
US-20080312337-A1 Anticancer Composition Comprising Obovatol or Obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2008-12-18 US disclosed
US-20080312337-A1 Anticancer Composition Comprising Obovatol or Obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2008-12-18 US disclosed
US-20080312337-A1 Anticancer Composition Comprising Obovatol or Obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2008-12-18 US disclosed
US-20080312337-A1 Anticancer Composition Comprising Obovatol or Obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2008-12-18 US disclosed
US-20070037889-A1 Anticancer composition comprising obovatol or obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2007-02-15 US disclosed
US-20070037889-A1 Anticancer composition comprising obovatol or obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2007-02-15 US disclosed
US-20070037889-A1 Anticancer composition comprising obovatol or obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2007-02-15 US disclosed
US-20070037889-A1 Anticancer composition comprising obovatol or obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2007-02-15 US disclosed
US-20070037889-A1 Anticancer composition comprising obovatol or obovatal KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2007-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312337-A1 Anticancer Composition Comprising Obovatol or Obovatal MMP2, MMP9, MMP7 MMP2 1/4885ESR1 3629/4885ESR2 1834/4885
US-20070037889-A1 Anticancer composition comprising obovatol or obovatal MMP2, MMP9, MMP7 MMP2 1/4885ESR1 3629/4885ESR2 1834/4885
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION COL2A1, COLGALT1, PLOD3 MMP2 392/4885ESR1 3665/4885ESR2 798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.