SCHEMBL3383602

SCHEMBL3383602

COc1c(CSC2=NOC(C)(C)C2)c(C(F)(F)F)nn1C

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31
MPO P05164 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1934015 0.88
SCHEMBL939073 0.87 MEN1 (0.30) MEN1KMT2ASMN1; SMN2
SCHEMBL3159705 0.85 GAA (0.30) GAA
SCHEMBL3383842 0.85
SCHEMBL3380689 0.85 MPO (0.43) GAAMPO
SCHEMBL3741118 0.84 CYP2C9 (0.33) GAAMPOMEN1KMT2ASMN1; SMN2
SCHEMBL1935019 0.84 GAA (0.32) GAAMPOMEN1KMT2ASMN1; SMN2
SCHEMBL19510500 0.82 GAA (0.33) GAAMPO
SCHEMBL3383844 0.81 CYP1A2 (0.34) MEN1KMT2ASMN1; SMN2
SCHEMBL3383487 0.81 LMNA (0.32) GAAMPOKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361225-A1 A PROCESS FOR PREPARATION OF 3-[5-(DIFLUOROMETHOXY)-1- METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-4- YLMETHYLSULFONYL]-4,5-DIHYDRO-5,5-DIMETHYL-1,2-OXAZOLE AND ITS INTERMEDIATES UPL LTD (IN) 2025-11-27 US disclosed
US-20240279212-A1 NOVEL INTERMEDIATE FOR PREPARATION OF PYROXASULFONE UPL LIMITED (IN) 2024-08-22 US disclosed
WO-2023194957-A1 A PROCESS FOR PREPARATION OF 3-[5-(DIFLUOROMETHOXY)-1- METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-4- YLMETHYLSULFONYL]-4,5-DIHYDRO-5,5-DIMETHYL-1,2-OXAZOLE AND ITS INTERMEDIATES UPL LIMITED (IN) 2023-10-12 WO disclosed
WO-2022249203-A1 NOVEL INTERMEDIATE FOR PREPARATION OF PYROXASULFONE UPL LIMITED (IN) 2022-12-01 WO disclosed
CN-112969697-A Process for producing herbicide and intermediate thereof 组合化学工业株式会社 2021-06-15 CN disclosed
EP-1364946-B1 ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2010-11-24 EP disclosed
US-7833939-B2 Herbicide compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-16 US disclosed
EP-2186410-A1 Isoxazoline derivative and herbicide comprising the same as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-05-19 EP disclosed
US-7238689-B2 Isoxazoline derivative and herbicide comprising the same as active ingredient IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2007-07-03 US disclosed
US-20050256004-A1 Herbicide compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-11-17 US disclosed
US-20040110749-A1 Isoxazoline derivative and herbicide comprising the same as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2004-06-10 US disclosed
EP-1364946-A1 ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2003-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250361225-A1 A PROCESS FOR PREPARATION OF 3-[5-(DIFLUOROMETHOXY)-1- METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-4- YLMETHYLSULFONYL]-4,5-DIHYDRO-5,5-DIMETHYL-1,2-OXAZOLE AND ITS INTERMEDIATES DHPS, DHODH, FIS1 GAA 3825/4885MPO 2447/4885MEN1 1388/4885
US-20050256004-A1 Herbicide compositions DDT, CYP4X1, GLRX3 GAA 1861/4885MPO 2230/4885MEN1 4458/4885
US-20240279212-A1 NOVEL INTERMEDIATE FOR PREPARATION OF PYROXASULFONE CYP11B1, CYP11B2, DHPS GAA 3244/4885MPO 332/4885MEN1 396/4885
US-20040110749-A1 Isoxazoline derivative and herbicide comprising the same as active ingredient CYP4X1, PRDX5, CYP3A7 GAA 2474/4885MPO 983/4885MEN1 4827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.