SCHEMBL3380689

SCHEMBL3380689

Cn1nc(C(F)(F)F)c(CSC2=NOC(C)(C)C2)c1F

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MPO P05164 1/20 0.43
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26514463 0.94 MPO (0.39) MPOGAA
SCHEMBL1935019 0.87 GAA (0.32) MPOGAA
SCHEMBL3741118 0.87 CYP2C9 (0.33) MPOGAA
SCHEMBL939811 0.86 MPO (0.40) MPOGAA
SCHEMBL3383602 0.85 GAA (0.31) MPOGAA
SCHEMBL19510500 0.85 GAA (0.33) MPOGAA
SCHEMBL3383487 0.84 LMNA (0.32) MPOGAA
SCHEMBL1934015 0.82
SCHEMBL3380850 0.81 ADAMTS5 (0.34)
SCHEMBL3159705 0.80 GAA (0.30) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022113-A1 Process for the Preparation of Pyroxasulfone ATTICUS LLC (US) 2026-01-22 US disclosed
US-20250361225-A1 A PROCESS FOR PREPARATION OF 3-[5-(DIFLUOROMETHOXY)-1- METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-4- YLMETHYLSULFONYL]-4,5-DIHYDRO-5,5-DIMETHYL-1,2-OXAZOLE AND ITS INTERMEDIATES UPL LTD (IN) 2025-11-27 US disclosed
US-20250361225-A1 A PROCESS FOR PREPARATION OF 3-[5-(DIFLUOROMETHOXY)-1- METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-4- YLMETHYLSULFONYL]-4,5-DIHYDRO-5,5-DIMETHYL-1,2-OXAZOLE AND ITS INTERMEDIATES UPL LTD (IN) 2025-11-27 US disclosed
US-20240279212-A1 NOVEL INTERMEDIATE FOR PREPARATION OF PYROXASULFONE UPL LIMITED (IN) 2024-08-22 US disclosed
WO-2023194957-A1 A PROCESS FOR PREPARATION OF 3-[5-(DIFLUOROMETHOXY)-1- METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-4- YLMETHYLSULFONYL]-4,5-DIHYDRO-5,5-DIMETHYL-1,2-OXAZOLE AND ITS INTERMEDIATES UPL LIMITED (IN) 2023-10-12 WO disclosed
WO-2023194957-A1 A PROCESS FOR PREPARATION OF 3-[5-(DIFLUOROMETHOXY)-1- METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-4- YLMETHYLSULFONYL]-4,5-DIHYDRO-5,5-DIMETHYL-1,2-OXAZOLE AND ITS INTERMEDIATES UPL LIMITED (IN) 2023-10-12 WO disclosed
WO-2023194957-A1 A PROCESS FOR PREPARATION OF 3-[5-(DIFLUOROMETHOXY)-1- METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-4- YLMETHYLSULFONYL]-4,5-DIHYDRO-5,5-DIMETHYL-1,2-OXAZOLE AND ITS INTERMEDIATES UPL LIMITED (IN) 2023-10-12 WO disclosed
WO-2022249203-A1 NOVEL INTERMEDIATE FOR PREPARATION OF PYROXASULFONE UPL LIMITED (IN) 2022-12-01 WO disclosed
US-20170179410-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-06-22 US disclosed
EP-1364946-B1 ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2010-11-24 EP disclosed
US-7833939-B2 Herbicide compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-16 US disclosed
EP-2186410-A1 Isoxazoline derivative and herbicide comprising the same as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-05-19 EP disclosed
US-7238689-B2 Isoxazoline derivative and herbicide comprising the same as active ingredient IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2007-07-03 US disclosed
US-20050256004-A1 Herbicide compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-11-17 US disclosed
US-20040110749-A1 Isoxazoline derivative and herbicide comprising the same as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2004-06-10 US disclosed
EP-1364946-A1 ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2003-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250361225-A1 A PROCESS FOR PREPARATION OF 3-[5-(DIFLUOROMETHOXY)-1- METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-4- YLMETHYLSULFONYL]-4,5-DIHYDRO-5,5-DIMETHYL-1,2-OXAZOLE AND ITS INTERMEDIATES DHPS, DHODH, FIS1 MPO 2447/4885GAA 3825/4885
US-20050256004-A1 Herbicide compositions DDT, CYP4X1, GLRX3 MPO 2230/4885GAA 1861/4885
US-20170179410-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NSD3, CCND3, DRD3 MPO 1546/4885GAA 4423/4885
US-20240279212-A1 NOVEL INTERMEDIATE FOR PREPARATION OF PYROXASULFONE CYP11B1, CYP11B2, DHPS MPO 332/4885GAA 3244/4885
US-20040110749-A1 Isoxazoline derivative and herbicide comprising the same as active ingredient CYP4X1, PRDX5, CYP3A7 MPO 983/4885GAA 2474/4885
US-20260022113-A1 Process for the Preparation of Pyroxasulfone AGXT, SLC6A5, CA2 MPO 780/4885GAA 413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.