SCHEMBL1935019

SCHEMBL1935019

Cn1nc(C(F)(F)F)c(CSC2=NOC(C)(C)C2)c1O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
MPO P05164 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3380689 0.87 MPO (0.43) GAAMPO
SCHEMBL938841 0.86 MEN1 (0.31) GAAMEN1KMT2ASMN1; SMN2
SCHEMBL3746264 0.86
SCHEMBL3741118 0.86 CYP2C9 (0.33) GAAMPOMEN1KMT2ASMN1; SMN2
SCHEMBL3383602 0.84 GAA (0.31) GAAMPOMEN1KMT2ASMN1; SMN2
SCHEMBL19510500 0.84 GAA (0.33) GAAMPO
SCHEMBL3383487 0.83 LMNA (0.32) GAAMPOKMT2A
SCHEMBL26514463 0.82 MPO (0.39) GAAMPOMEN1KMT2ASMN1; SMN2
SCHEMBL4026385 0.82 ADAMTS5 (0.34) GAA
SCHEMBL1934015 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036711-A Pyricularia sulfone Synthesis method of intermediate 山东潍坊润丰化工股份有限公司 2026-05-15 CN claimed
CN-122036711-A Pyricularia sulfone Synthesis method of intermediate 山东潍坊润丰化工股份有限公司 2026-05-15 CN disclosed
CN-115335375-B Process and intermediates for preparing penoxsulam 安道麦阿甘有限公司 2026-05-15 CN disclosed
US-20260022113-A1 Process for the Preparation of Pyroxasulfone ATTICUS LLC (US) 2026-01-22 US disclosed
US-20250361225-A1 A PROCESS FOR PREPARATION OF 3-[5-(DIFLUOROMETHOXY)-1- METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-4- YLMETHYLSULFONYL]-4,5-DIHYDRO-5,5-DIMETHYL-1,2-OXAZOLE AND ITS INTERMEDIATES UPL LTD (IN) 2025-11-27 US disclosed
CN-114450270-B Preparation method and intermediate of metazopyr 安道麦阿甘有限公司 2025-05-06 CN disclosed
US-20240279212-A1 NOVEL INTERMEDIATE FOR PREPARATION OF PYROXASULFONE UPL LIMITED (IN) 2024-08-22 US disclosed
CN-117658938-A Method for preparing metazopyr intermediate and application thereof 启农生物科技(北京)有限公司 2024-03-08 CN disclosed
CN-117624153-A Synthesis method of 4- [ [ (4, 5-dihydro-5, 5-dimethyl-3-isoxazolyl) thio ] methyl ] -1-methyl-3- (trifluoromethyl) -1H-pyrazol-5-ol 山东润博生物科技有限公司 2024-03-01 CN disclosed
CN-117624153-A Synthesis method of 4- [ [ (4, 5-dihydro-5, 5-dimethyl-3-isoxazolyl) thio ] methyl ] -1-methyl-3- (trifluoromethyl) -1H-pyrazol-5-ol 山东润博生物科技有限公司 2024-03-01 CN disclosed
EP-1364946-B1 ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2010-11-24 EP disclosed
US-7833939-B2 Herbicide compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-16 US disclosed
EP-2186410-A1 Isoxazoline derivative and herbicide comprising the same as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-05-19 EP disclosed
US-7488831-B2 Process for producing 5-hydroxy-4-thiomethylpyrazole compound IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2009-02-10 US disclosed
US-20070185334-A1 Process for producing 5-hydroxy-4-thiomethylpyrazole compound KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-08-09 US disclosed
US-7238689-B2 Isoxazoline derivative and herbicide comprising the same as active ingredient IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2007-07-03 US disclosed
EP-1767528-A1 PROCESS FOR PRODUCING 5-HYDROXY-4-THIOMETHYLPYRAZOLE COMPOUND IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 2007-03-28 EP disclosed
US-20050256004-A1 Herbicide compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-11-17 US disclosed
US-20040110749-A1 Isoxazoline derivative and herbicide comprising the same as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2004-06-10 US disclosed
EP-1364946-A1 ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2003-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250361225-A1 A PROCESS FOR PREPARATION OF 3-[5-(DIFLUOROMETHOXY)-1- METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-4- YLMETHYLSULFONYL]-4,5-DIHYDRO-5,5-DIMETHYL-1,2-OXAZOLE AND ITS INTERMEDIATES DHPS, DHODH, FIS1 GAA 3825/4885MPO 2447/4885MEN1 1388/4885
US-20050256004-A1 Herbicide compositions DDT, CYP4X1, GLRX3 GAA 1861/4885MPO 2230/4885MEN1 4458/4885
US-20070185334-A1 Process for producing 5-hydroxy-4-thiomethylpyrazole compound CYP3A5, CYP4F11, GTF3C5 GAA 595/4885MPO 989/4885MEN1 4454/4885
US-20240279212-A1 NOVEL INTERMEDIATE FOR PREPARATION OF PYROXASULFONE CYP11B1, CYP11B2, DHPS GAA 3244/4885MPO 332/4885MEN1 396/4885
US-20040110749-A1 Isoxazoline derivative and herbicide comprising the same as active ingredient CYP4X1, PRDX5, CYP3A7 GAA 2474/4885MPO 983/4885MEN1 4827/4885
US-20260022113-A1 Process for the Preparation of Pyroxasulfone AGXT, SLC6A5, CA2 GAA 413/4885MPO 780/4885MEN1 4292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.