SCHEMBL338467

SCHEMBL338467

[CH]c1ccccc1OC(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.47
CYP1A2 P05177 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALDH1A1 P00352 2/20 0.44
ACHE P22303 1/20 0.44
NISCH Q9Y2I1 2/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
TLR8 Q9NR97 1/20 0.39
MCHR1 Q99705 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA7 P43166 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL338466 1.00 IRAK4 (0.47) IRAK4CYP1A2MAPTCYP2C9CYP2C19
SCHEMBL11382835 0.82 CA1 (0.39) IRAK4CYP1A2MAPTCYP2C9CYP2C19
SCHEMBL2069775 0.82 ALDH1A1 (0.57) IRAK4CYP1A2MAPTCYP2C9CYP2C19
SCHEMBL29591819 0.82 ALDH1A1 (0.57) IRAK4CYP1A2MAPTCYP2C9CYP2C19
SCHEMBL5803755 0.76 DRD1 (0.42) MAPTALDH1A1KDM4EPOLBKMT2A
SCHEMBL31634047 0.75 IRAK4 (0.50) IRAK4CYP1A2MAPTCYP2C9CYP2C19
SCHEMBL3632568 0.75 IRAK4 (0.50) IRAK4CYP1A2MAPTCYP2C9CYP2C19
SCHEMBL28851801 0.75 ALDH1A1 (0.52) IRAK4CYP1A2MAPTCYP2C9CYP2C19
SCHEMBL677274 0.74 MCHR1 (0.46) IRAK4CYP1A2MAPTCYP2C9CYP2C19
SCHEMBL339091 0.74 ACLY (0.40) IRAK4CYP1A2MAPTCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063678-A Synthesis method of acid-resistant degradable gel composite temporary plugging agent 中国石油天然气股份有限公司 2024-05-24 CN claimed
CN-117858964-A Flow cell 因美纳有限公司 2024-04-09 CN claimed
CN-114573760-B Prepolymer, resin composition comprising the same, and articles thereof 台光电子材料股份有限公司 2024-01-26 CN claimed
CN-116947695-A Preparation method and application of 1,3, 6-hexanetrinitrile 上海如鲲新材料股份有限公司 2023-10-27 CN claimed
CN-114573760-A Prepolymers, resin compositions containing prepolymers, and articles thereof 台光电子材料股份有限公司 2022-06-03 CN claimed
CN-107628979-B Method for synthesizing 2H-azacyclo acrylamide 南京工业大学 2020-04-14 CN claimed
US-9315748-B2 Cold flow additives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2016-04-19 US claimed
US-8846587-B2 Functionalized monomers and polymers ELEVANCE RENEWABLE SCIENCES, INC. (US) 2014-09-30 US claimed
EP-2721106-A2 ADHESION PROMOTERS AND GEL-MODIFIERS FOR OLEFIN METATHESIS COMPOSITIONS Materia, Inc. (US) 2014-04-23 EP claimed
EP-2694628-A1 COLD FLOW ADDITIVES FOR FUELS Elevance Renewable Sciences, Inc. (US) 2014-02-12 EP claimed
WO-2012129482-A2 FUNCTIONALIZED MONOMERS ELEVANCE RENEWABLE SCIENCES (US) 2012-09-27 WO claimed
WO-2012129477-A1 FUNCTIONALIZED MONOMERS ELEVANCE RENEWABLE SCIENCES (US) 2012-09-27 WO claimed
US-20120245063-A1 FUNCTIONALIZED MONOMERS AND POLYMERS WILMAR TRADING PTE LTD (SG) 2012-09-27 US claimed
WO-2012128788-A1 FUNCTIONALIZED MONOMERS AND POLYMERS ELEVANCE RENEWABLE SCIENCES, INC. (US) 2012-09-27 WO claimed
WO-2012129479-A2 MALIENATED DERIVATIVES ELEVANCE RENEWABLE SCIENCES (US) 2012-09-27 WO claimed
EP-2496628-A1 METHOD FOR PRODUCING AN AQUEOUS POLYMER DISPERSION BASF SE (DE) 2012-09-12 EP claimed
US-20120208959-A1 METHOD FOR PRODUCING AN AQUEOUS POLYMER DISPERSION BASF SE (DE) 2012-08-16 US claimed
US-20120149840-A1 PROCESS FOR PRODUCING AN AQUEOUS POLYMER DISPERSION Univ. of Southern Mississippi Res. Foundation (US) 2012-06-14 US claimed
WO-2012076426-A1 METHOD FOR PRODUCING AN AQUEOUS POLYMER PRODUCT DISPERSION BASF SE (DE) 2012-06-14 WO claimed
WO-2011051374-A1 METHOD FOR PRODUCING AN AQUEOUS POLYMER DISPERSION BASF SE (DE) 2011-05-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149840-A1 PROCESS FOR PRODUCING AN AQUEOUS POLYMER DISPERSION PUF60, PARG, ACMSD IRAK4 3459/4885CYP1A2 648/4885MAPT 68/4885
US-20120245063-A1 FUNCTIONALIZED MONOMERS AND POLYMERS PUF60, FGB, MSN IRAK4 2778/4885CYP1A2 1411/4885MAPT 1386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.