Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338467 | 1.00 | IRAK4 (0.47) | IRAK4CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL11382835 | 0.82 | CA1 (0.39) | IRAK4CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL2069775 | 0.82 | ALDH1A1 (0.57) | IRAK4CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL29591819 | 0.82 | ALDH1A1 (0.57) | IRAK4CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL5803755 | 0.76 | DRD1 (0.42) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL31634047 | 0.75 | IRAK4 (0.50) | IRAK4CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL3632568 | 0.75 | IRAK4 (0.50) | IRAK4CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL28851801 | 0.75 | ALDH1A1 (0.52) | IRAK4CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL677274 | 0.74 | MCHR1 (0.46) | IRAK4CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL339091 | 0.74 | ACLY (0.40) | IRAK4CYP1A2MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240229300-A9 | POLYMER FIBERS AND PARTICLES PRODUCED BY ELECTROSPINNING OR ELECTROSPRAYING | SCALE HOLDINGS LLC | 2024-07-11 | — | — | US | disclosed |
| US-20240133079-A1 | POLYMER FIBERS AND PARTICLES PRODUCED BY ELECTROSPINNING OR ELECTROSPRAYING | SCALE HOLDINGS LLC (US) | 2024-04-25 | — | — | US | disclosed |
| WO-2024086429-A1 | POLYMER FIBERS AND PARTICLES PRODUCED BY ELECTROSPINNING OR ELECTROSPRAYING | SCALE HOLDINGS LLC (US) | 2024-04-25 | — | — | WO | disclosed |
| US-11821112-B1 | Polymer fibers and particles produced by electrospinning or electrospraying | SCALE HOLDINGS LLC (US) | 2023-11-21 | — | — | US | disclosed |
| US-10329245-B2 | Method for making a prenyl group-substituted tyrosine compound | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2019-06-25 | — | — | US | disclosed |
| US-20180208546-A1 | METHOD FOR MAKING A PRENYL GROUP-SUBSTITUTED TYROSINE COMPOUND | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2018-07-26 | — | — | US | disclosed |
| US-10023527-B2 | Uncatalyzed sigmatropic rearrangement of tyrosine-based compounds | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2018-07-17 | — | — | US | disclosed |
| EP-1905777-B2 | RUTHENIUM COMPLEX LIGAND, RUTHENIUM COMPLEX, CARRIED RUTHENIUM COMPLEX CATALYST AND THE PREPARING METHODS AND THE USE THEREOF | ZANNAN SCITECH CO LTD (CN) | 2018-06-27 | — | — | EP | disclosed |
| US-20170217877-A1 | UNCATALYZED SIGMATROPIC REARRANGEMENT OF TYROSINE-BASED COMPOUNDS | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2017-08-03 | — | — | US | disclosed |
| US-9688611-B2 | Synthesis of (S)-2-acetamido-3-(4-hydroxy-3-(3-methylbut-2-enyl) phenyl) propanoic acid derivatives | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2017-06-27 | — | — | US | disclosed |
| US-20080139861-A1 | Metathesis catalysts | ARLANXEO DEUTSCHLAND GMBH (DE) | 2008-06-12 | — | — | US | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1905777-A1 | RUTHENIUM COMPLEX LIGAND, RUTHENIUM COMPLEX, CARRIED RUTHENIUM COMPLEX CATALYST AND THE PREPARING METHODS AND THE USE THEREOF | Zhan, Zheng-Yun (CN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007054483-A1 | PREPARATION OF CATALYSTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-18 | — | — | WO | disclosed |
| US-20070043180-A1 | Recyclable ruthenium catalysts for metathesis reactions | ZHENG-YUN JAMES ZHAN (CN) | 2007-02-22 | — | — | US | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-20040176608-A1 | Novel transition-metal complexes and use thereof in transition-metal catalyzed reactions | BAYER CHEMICALS AG (DE) | 2004-09-09 | — | — | US | disclosed |
| US-20040087438-A1 | Metathesis catalysts | ARLANXEO DEUTSCHLAND GMBH (DE) | 2004-05-06 | — | — | US | disclosed |
| US-20030220512-A1 | Novel transition metal complexes and their use in transition metal-catalysed reactions | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208546-A1 | METHOD FOR MAKING A PRENYL GROUP-SUBSTITUTED TYROSINE COMPOUND | BAX, CD40, CASP3 | IRAK4 1062/4885CYP1A2 856/4885MAPT 144/4885 |
| US-20040176608-A1 | Novel transition-metal complexes and use thereof in transition-metal catalyzed reactions | AP1M1, SOD1, INTS9 | IRAK4 3698/4885CYP1A2 133/4885MAPT 2516/4885 |
| US-20080139861-A1 | Metathesis catalysts | PPOX, PIN4, ICMT | IRAK4 4467/4885CYP1A2 259/4885MAPT 837/4885 |
| US-20030220512-A1 | Novel transition metal complexes and their use in transition metal-catalysed reactions | AP1M1, AP3M1, CYC1 | IRAK4 4025/4885CYP1A2 93/4885MAPT 2485/4885 |
| US-20170217877-A1 | UNCATALYZED SIGMATROPIC REARRANGEMENT OF TYROSINE-BASED COMPOUNDS | BAX, CD40, CASP3 | IRAK4 1587/4885CYP1A2 810/4885MAPT 100/4885 |
| US-10329245-B2 | Method for making a prenyl group-substituted tyrosine compound | BAX, CD40, CASP3 | IRAK4 1062/4885CYP1A2 856/4885MAPT 144/4885 |
| US-10023527-B2 | Uncatalyzed sigmatropic rearrangement of tyrosine-based compounds | BAX, CD40, CASP3 | IRAK4 1587/4885CYP1A2 810/4885MAPT 100/4885 |
| US-20070043180-A1 | Recyclable ruthenium catalysts for metathesis reactions | RPIA, REV1, RCSD1 | IRAK4 1573/4885CYP1A2 486/4885MAPT 2838/4885 |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | IRAK4 735/4885CYP1A2 420/4885MAPT 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.