Naphthalene

Naphthalene

SCHEMBL338629

c1c[nH]cn1.c1ccc2ccccc2c1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.65
FKBP5 Q13451 1/20 0.65
CYP2A6 P11509 1/20 0.40
ALOX12 P18054 1/20 0.40
CYP11B1 P15538 3/20 0.34
CYP11B2 P19099 3/20 0.34
CYP19A1 P11511 2/20 0.32
MAPK8 P45983 1/20 0.32
MAPK9 P45984 1/20 0.32
MAPK10 P53779 1/20 0.32
CYP17A1 P05093 1/20 0.32
AXL P30530 1/20 0.32
NUDT1 P36639 1/20 0.32
TRPA1 O75762 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
ITGB2 P05107 1/20 0.32
ICAM1 P05362 1/20 0.32
ITGAL P20701 1/20 0.32
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL2123892 1.00 ALDH1A1 (0.65) ALDH1A1FKBP5CYP2A6ALOX12CYP11B1
Naphthalene SCHEMBL27481708 0.98 ALDH1A1 (0.62) ALDH1A1FKBP5CYP2A6ALOX12CYP11B1
Anthracene SCHEMBL28457231 0.91 ALDH1A1 (0.59) ALDH1A1FKBP5CYP2A6CYP11B1CYP11B2
Anthracene SCHEMBL28211461 0.91 ALDH1A1 (0.59) ALDH1A1FKBP5CYP2A6CYP11B1CYP11B2
Imidazole SCHEMBL26982228 0.89 ALDH1A1 (0.56) ALDH1A1FKBP5
Isoquinoline SCHEMBL2639468 0.88 ALDH1A1 (0.50) ALDH1A1FKBP5CYP11B1CYP11B2CYP19A1
Phenanthrene SCHEMBL1673168 0.87 ALDH1A1 (0.54) ALDH1A1FKBP5CYP2A6ADRA2A
Naphthalene SCHEMBL10693189 0.86 ALDH1A1 (0.48) ALDH1A1FKBP5AHRADRA2A
Phenazine SCHEMBL28557583 0.86 ALDH1A1 (0.59) ALDH1A1FKBP5ADRA2ASLC6A2
Pyrene SCHEMBL16568699 0.84 ALDH1A1 (0.56) ALDH1A1FKBP5AHRHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024016963-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND USE THEREOF 广东阿格蕾雅光电材料有限公司 2024-01-25 WO claimed
WO-2023138254-A1 HETEROCYCLIC COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL AND ELEMENT 上海八亿时空先进材料有限公司 2023-07-27 WO claimed
US-11702546-B2 Near-infrared heptamethine dyes for generation of singlet oxygen CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-07-18 US claimed
US-20230173071-A1 TREATMENT OF MYOPIA AND OTHER OCULAR CONDITIONS USING SINGLET OXYGEN GENERATED FROM DYES ACTIVATED BY NEAR-INFRARED LIGHT CALIFORNIA INST OF TECHN (US) 2023-06-08 US claimed
CN-113286788-A Treatment of myopia and other eye disorders using singlet oxygen 加州理工学院 2021-08-20 CN claimed
US-20200131370-A1 Near-Infrared Heptamethine Dyes For Generation Of Singlet Oxygen CALIFORNIA INSTITUTE OF TECHNOLOGY 2020-04-30 US claimed
US-20200129620-A1 Treatment Of Myopia And Other Ocular Conditions Using Singlet Oxygen Generated From Dyes Activated By Near-Infrared Light CALIFORNIA INSTITUTE OF TECHNOLOGY 2020-04-30 US claimed
CN-105936669-B One kind being based on the porous super-molecule assembling body and preparation method thereof of cucurbit [8] urea 南开大学 2019-01-18 CN claimed
CN-106715420-A crosslinkable host material 西诺拉股份有限公司 2017-05-24 CN claimed
CN-102482296-B Schiff's base type compound and the dye material containing this compound ADEKA CORP. (JP) 2015-11-25 CN claimed
US-5410030-A Nucleic acid stains MOLECULAR PROBES, INC. (US) 1995-04-25 US claimed
US-4792508-A STEREOISOMERIC NAPHTHALENE IMIDAZOLE PERYLENES, ARYL AMINES XEROX CORPORATION (US) 1988-12-20 US claimed
US-12544322-B2 Dyeing composition comprising an anthraquinone cationic direct dye, a polyol, an anionic surfactant and a nonionic polysaccharide L'ORÉAL (FR) 2026-02-10 US disclosed
US-12533303-B2 Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition L'OREAL (FR) 2026-01-27 US disclosed
US-20260007583-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION OREAL (FR) 2026-01-08 US disclosed
US-20250381107-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION OREAL (FR) 2025-12-18 US disclosed
US-4863845-A SHELL-CORE PARTICLES, CRYSTAL STRUCTURE OR PARTICLE SIZE CHANGE FUJI PHOTO FILM CO., LTD. (JP) 1989-09-05 US disclosed
US-4713321-A SENSITIZING DYES, OXIDIZERS SUCH AS PEROXIDES FUJI PHOTO FILM CO., LTD. (JP) 1987-12-15 US disclosed
EP-0185100-A1 PROCESS FOR PREPARING SILVER HALIDE EMULSION FUJI PHOTO FILM CO., LTD. (JP) 1986-06-25 EP disclosed
EP-0164760-A2 Internal latent image type direct positive silver halide emulsion and process for producing the same FUJI PHOTO FILM CO., LTD. (JP) 1985-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533303-B2 Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition KRT18, CA12, CA7 ALDH1A1 1626/4885FKBP5 1885/4885CYP2A6 1793/4885
US-20260007583-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION KRT18, F12, VIM ALDH1A1 1427/4885FKBP5 4081/4885CYP2A6 1916/4885
US-20200129620-A1 Treatment Of Myopia And Other Ocular Conditions Using Singlet Oxygen Generated From Dyes Activated By Near-Infrared Light CRY1, MYH10, MYLK ALDH1A1 1652/4885FKBP5 894/4885CYP2A6 2287/4885
US-12544322-B2 Dyeing composition comprising an anthraquinone cationic direct dye, a polyol, an anionic surfactant and a nonionic polysaccharide KRT18, DSG1, S100A10 ALDH1A1 1172/4885FKBP5 3361/4885CYP2A6 1756/4885
US-20250381107-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION KRT18, VIM, MAP1LC3A ALDH1A1 739/4885FKBP5 3340/4885CYP2A6 1711/4885
US-20230173071-A1 TREATMENT OF MYOPIA AND OTHER OCULAR CONDITIONS USING SINGLET OXYGEN GENERATED FROM DYES ACTIVATED BY NEAR-INFRARED LIGHT CRY1, MYH10, MYLK ALDH1A1 1652/4885FKBP5 894/4885CYP2A6 2287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.