Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390541 | 0.87 | ALDH1A1 (0.42) | LMNAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL3395053 | 0.74 | ALDH1A1 (0.48) | LMNAALDH1A1CA12CA1CA2 | |
| SCHEMBL3392363 | 0.72 | KDM4E (0.43) | LMNAHSD17B10KDM4ECA12CA1 | |
| SCHEMBL6690666 | 0.72 | ALDH1A1 (0.42) | LMNAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL6687177 | 0.68 | GAA (0.35) | LMNAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL1522527 | 0.67 | HSD17B10 (0.37) | LMNAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL8683168 | 0.65 | CA12 (0.55) | LMNAALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL8286607 | 0.65 | CA12 (0.53) | LMNAALDH1A1HSD17B10KDM4ECA12 | |
| SCHEMBL3394006 | 0.63 | AGBL2 (0.33) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL390919 | 0.62 | ALDH1A1 (0.65) | LMNAALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | LMNA 3232/4885ALDH1A1 1434/4885HSD17B10 1232/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | LMNA 4000/4885ALDH1A1 891/4885HSD17B10 1422/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | LMNA 4225/4885ALDH1A1 1592/4885HSD17B10 1335/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | LMNA 3232/4885ALDH1A1 1434/4885HSD17B10 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.