Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461902 | 0.80 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL17104893 | 0.76 | RAB9A (0.55) | RAB9ASMN1; SMN2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29022910 | 0.71 | CYP1A2 (0.42) | SMN1; SMN2POLBGRM5ALDH1A1HTT | |
| SCHEMBL12075261 | 0.70 | POLB (0.50) | RAB9ASMN1; SMN2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2211763 | 0.69 | KDM4E (0.46) | RAB9ASMN1; SMN2POLBALDH1A1HTT | |
| SCHEMBL31436278 | 0.68 | SMN1; SMN2 (0.42) | RAB9ASMN1; SMN2GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL5189603 | 0.67 | KDM4E (0.44) | RAB9ASMN1; SMN2POLBALDH1A1HTT | |
| SCHEMBL11117869 | 0.67 | POLB (0.47) | RAB9ASMN1; SMN2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL16114651 | 0.67 | NOS3 (0.39) | RAB9AALDH1A1HTTKDM4E | |
| SCHEMBL16114653 | 0.67 | P2RX7 (0.37) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664396-B2 | Photoluminescent metal complexes for protein staining | BIO-RAD LABORATORIES, INC. (US) | 2014-03-04 | — | — | US | disclosed |
| US-8664396-B2 | Photoluminescent metal complexes for protein staining | BIO-RAD LABORATORIES, INC. (US) | 2014-03-04 | — | — | US | disclosed |
| EP-2217608-B1 | PHOTOLUMINESCENT METAL COMPLEXES FOR PROTEIN STAINING | BIO RAD LABORATORIES (US) | 2012-09-05 | — | — | EP | disclosed |
| EP-1809620-B1 | NOVEL TETRAZOLE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2010-12-29 | — | — | EP | disclosed |
| US-20100144046-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | BIO-RAD LABORATORIES, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| US-20100144046-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | BIO-RAD LABORATORIES, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| WO-2010065514-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | BIO-RAD LABORATORIES, INC. (US) | 2010-06-10 | — | — | WO | disclosed |
| WO-2009067603-A1 | PHOTOLUMINESCENT METAL COMPLEXES FOR PROTEIN STAINING | BIO-RAD LABORATORIES, INC. (US) | 2009-05-28 | — | — | WO | disclosed |
| US-20090131640-A1 | PHOTOLUMINESCENT METAL COMPLEXES FOR PROTEIN STAINING | BIO-RAD LABORATORIES, INC. (US) | 2009-05-21 | — | — | US | disclosed |
| US-20090131640-A1 | PHOTOLUMINESCENT METAL COMPLEXES FOR PROTEIN STAINING | BIO-RAD LABORATORIES, INC. (US) | 2009-05-21 | — | — | US | disclosed |
| US-20070299110-A1 | Novel Tetrazole Derivatives as Positive Allosteric Modulators of Metabotropic Glutamate | ADDEX PHARMACEUTICALS SA (CH) | 2007-12-27 | — | — | US | disclosed |
| EP-1809620-A1 | NOVEL TETRAZOLE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Addex Pharma SA (CH) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006048771-A1 | NOVEL TETRAZOLE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2006-05-11 | — | — | WO | disclosed |
| WO-2003027095-A1 | SUBSTITUTED 3-PYRIDYL TETRAZOLES AS STEROID C17,20 LYASE INHIBITORS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299110-A1 | Novel Tetrazole Derivatives as Positive Allosteric Modulators of Metabotropic Glutamate | GRM5, GRIK5, GRM1 | RAB9A 1426/4885SMN1; SMN2 2141/4885GRIN2D 26/4885 |
| US-20090131640-A1 | PHOTOLUMINESCENT METAL COMPLEXES FOR PROTEIN STAINING | NR2E3, NR2C2, ORC3 | RAB9A 4244/4885SMN1; SMN2 4400/4885GRIN2D 245/4885 |
| US-20100144046-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | CAD, NCLN, CCL5 | RAB9A 4443/4885SMN1; SMN2 3685/4885GRIN2D 2220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.