SCHEMBL3394969

SCHEMBL3394969

NN(c1ccccc1)c1ncncn1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.33
ALDH1A1 P00352 4/20 0.32
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
MAPT P10636 3/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2D6 P10635 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TSHR P16473 2/20 0.32
ATR Q13535 1/20 0.31
EGFR P00533 2/20 0.31
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4155171 0.84 NOS3 (0.39) HSP90AA1ALDH1A1TDP1L3MBTL1MAPT
SCHEMBL11395064 0.78 ALDH1A1 (0.36) ALDH1A1TDP1L3MBTL1MAPTEGFR
SCHEMBL2856484 0.77 CSF1R (0.40) TSHREGFRMEN1KMT2A
SCHEMBL4399532 0.77 ALDH1A1 (0.48) ALDH1A1TDP1L3MBTL1MAPTCYP1A2
SCHEMBL7511419 0.77 ALDH1A1 (0.41) ALDH1A1TDP1L3MBTL1MAPTCYP1A2
SCHEMBL5959630 0.74 ALDH1A1 (0.34) HSP90AA1ALDH1A1TDP1L3MBTL1MAPT
SCHEMBL795930 0.74 EGFR (0.46) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL6480214 0.74 CYP2D6 (0.38) ALDH1A1TDP1L3MBTL1CYP1A2CYP2D6
SCHEMBL1792016 0.72 ALDH1A1 (0.46) HSP90AA1ALDH1A1TDP1L3MBTL1MAPT
SCHEMBL193916 0.72 ALDH1A1 (0.46) HSP90AA1ALDH1A1TDP1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165526-A1 METHOD FOR PREPARING SUBSTITUTED TRIAZINES UNIROYAL CHEMICAL COMPANY, Inc. (US) 2002-01-02 EP claimed
WO-2000061567-A1 METHOD FOR PREPARING SUBSTITUTED TRIAZINES UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-10-19 WO claimed
US-5990310-A REACTING A PHENYLAZOANILINE WITH A CYANURIC HALIDE AND REDUCING THE PHENYLAZOPHENYLAMINO-S-TRIAZINE TO PRODUCE AN AMINOANILINO-S-TRIAZINE FOLLOWED BY ALKYLATION; OZONE RESISTANCE; ANTISOILANTS; DISCOLORATION INHIBITION UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-11-23 US claimed
EP-2481730-B1 Insecticidal (1,3,5)-triazinyl phenyl hydrazones DOW AGROSCIENCES LLC (US) 2013-12-18 EP disclosed
EP-2481731-B1 Insecticidal (1,3,5)-triazinyl phenyl hydrazones DOW AGROSCIENCES LLC (US) 2013-10-23 EP disclosed
EP-2481730-A1 Insecticidal (1,3,5)-triazinyl phenyl hydrazones Dow AgroSciences LLC (US) 2012-08-01 EP disclosed
EP-2481731-A1 Insecticidal (1,3,5)-triazinyl phenyl hydrazones Dow AgroSciences LLC (US) 2012-08-01 EP disclosed
EP-2197857-A2 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES Dow AgroSciences LLC (US) 2010-06-23 EP disclosed
WO-2009048750-A3 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES DOW AGROSCIENCES LLC (US) 2009-05-28 WO disclosed
WO-2009048750-A2 INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES DOW AGROSCIENCES LLC (US) 2009-04-16 WO disclosed
EP-1727807-B1 ANTIOZONANT BASED FUNCTIONALIZED BENZOTRIAZOLE UV ABSORBERS AND THE PROCESS THEREOF COUNCIL SCIENT IND RES (IN) 2007-07-18 EP disclosed
US-7211675-B2 Antiozonant based on functionalized benzotriazole UV absorbers and the process thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2007-05-01 US disclosed
US-20050143584-A1 Antiozonant based on functionalized benzotriazole UV absorbers and the process thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-06-30 US disclosed
EP-1165526-A1 METHOD FOR PREPARING SUBSTITUTED TRIAZINES UNIROYAL CHEMICAL COMPANY, Inc. (US) 2002-01-02 EP disclosed
EP-1165526-A1 METHOD FOR PREPARING SUBSTITUTED TRIAZINES UNIROYAL CHEMICAL COMPANY, Inc. (US) 2002-01-02 EP disclosed
WO-2000061567-A1 METHOD FOR PREPARING SUBSTITUTED TRIAZINES UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-10-19 WO disclosed
WO-2000061567-A1 METHOD FOR PREPARING SUBSTITUTED TRIAZINES UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-10-19 WO disclosed
US-5990310-A REACTING A PHENYLAZOANILINE WITH A CYANURIC HALIDE AND REDUCING THE PHENYLAZOPHENYLAMINO-S-TRIAZINE TO PRODUCE AN AMINOANILINO-S-TRIAZINE FOLLOWED BY ALKYLATION; OZONE RESISTANCE; ANTISOILANTS; DISCOLORATION INHIBITION UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-11-23 US disclosed
US-5990310-A REACTING A PHENYLAZOANILINE WITH A CYANURIC HALIDE AND REDUCING THE PHENYLAZOPHENYLAMINO-S-TRIAZINE TO PRODUCE AN AMINOANILINO-S-TRIAZINE FOLLOWED BY ALKYLATION; OZONE RESISTANCE; ANTISOILANTS; DISCOLORATION INHIBITION UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050143584-A1 Antiozonant based on functionalized benzotriazole UV absorbers and the process thereof SULT1A1, AOX1, XDH HSP90AA1 1961/4885ALDH1A1 328/4885TDP1 1901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.