Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 9/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426586 | 0.82 | JAK2 (0.35) | GRM5KCNH2F2TGFBR1 | |
| SCHEMBL3395630 | 0.82 | HDAC6 (0.44) | GRM5F2 | |
| SCHEMBL3392233 | 0.81 | PTGER4 (0.39) | GRM5SCDSCD5F2NPC1 | |
| SCHEMBL3397017 | 0.77 | PKM (0.37) | NPC1 | |
| SCHEMBL3431052 | 0.76 | CNR1 (0.37) | GRM5 | |
| SCHEMBL3395670 | 0.70 | SORT1 (0.32) | GRM5F2 | |
| SCHEMBL3394445 | 0.69 | ALPL (0.43) | NPC1RXFP1 | |
| SCHEMBL3395758 | 0.69 | GRK6 (0.41) | — | |
| SCHEMBL3394902 | 0.68 | GSK3B (0.39) | — | |
| SCHEMBL13425918 | 0.67 | TRPA1 (0.38) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |