Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31326803 | 0.85 | KIF11 (0.49) | ALDH1A1HSD17B10KIF11S1PR1PTAFR | |
| SCHEMBL841200 | 0.85 | KIF11 (0.49) | ALDH1A1HSD17B10KIF11S1PR1PTAFR | |
| SCHEMBL23610039 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KIF11S1PR1RXRA | |
| SCHEMBL31115680 | 0.85 | KIF11 (0.52) | ALDH1A1KIF11PTAFRRXRARXRB | |
| SCHEMBL398678 | 0.81 | ADORA2A (0.54) | ALDH1A1HSD17B10NPC1RAB9APTPN5 | |
| Hydrogen Sulfide SCHEMBL27798476 | 0.81 | KIF11 (0.52) | ALDH1A1KIF11PTAFRRXRARXRB | |
| SCHEMBL28975155 | 0.81 | KIF11 (0.52) | ALDH1A1KIF11S1PR1PTAFRRXRA | |
| SCHEMBL30284747 | 0.81 | KIF11 (0.52) | ALDH1A1KIF11S1PR1PTAFRRXRA | |
| SCHEMBL31754131 | 0.80 | KIF11 (0.47) | ALDH1A1KIF11PTAFRRXRARXRB | |
| SCHEMBL23421772 | 0.80 | CNR1 (0.49) | ALDH1A1HSD17B10S1PR1PTAFRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122857-A1 | HETEROBICYCLIC CARBOXAMIDES AS INHIBITORS FOR KINASES | NOVARTIS AG (CH) | 2012-05-17 | — | — | US | claimed |
| US-20100029626-A1 | Cyclic sulfones useful as mitochondrial sodium-calcium exchangers | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | claimed |
| EP-1996558-A1 | HETEROBICYCLIC CARBOXAMIDES AS INHIBITORS FOR KINASES | Novartis AG (CH) | 2008-12-03 | — | — | EP | claimed |
| WO-2007104538-A1 | HETEROBICYCLIC CARBOXAMIDES AS INHIBITORS FOR KINASES | NOVARTIS AG (CH) | 2007-09-20 | — | — | WO | claimed |
| EP-2248868-B1 | LUMINESCENT ELEMENT MATERIAL AND LUMINESCENT ELEMENT | TORAY INDUSTRIES (JP) | 2018-09-19 | — | — | EP | disclosed |
| EP-2248868-A1 | LUMINESCENT ELEMENT MATERIAL AND LUMINESCENT ELEMENT | Toray Industries, Inc. (JP) | 2010-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029626-A1 | Cyclic sulfones useful as mitochondrial sodium-calcium exchangers | SLC8B1, MCU, GLS | ALDH1A1 2955/4885HSD17B10 2330/4885KIF11 2748/4885 |
| US-20120122857-A1 | HETEROBICYCLIC CARBOXAMIDES AS INHIBITORS FOR KINASES | MAP3K20, PHKG1, PHKG2 | ALDH1A1 4102/4885HSD17B10 3043/4885KIF11 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.