SCHEMBL3402830

SCHEMBL3402830

c1cnc2ncn3cnnc3c2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
CYP1A2 P05177 2/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
ALPG P10696 1/20 0.45
HSD17B10 Q99714 1/20 0.45
HTT P42858 3/20 0.37
CYP2C9 P11712 1/20 0.37
MAPK1 P28482 1/20 0.37
CYP2C19 P33261 1/20 0.37
ATM Q13315 1/20 0.37
HRH4 Q9H3N8 2/20 0.36
TRPA1 O75762 1/20 0.34
LMNA P02545 1/20 0.34
MAOB P27338 3/20 0.33
MAPT P10636 1/20 0.33
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15644331 0.76 NUDT1 (0.35) KDM4EKMT2ALMNAMAOBMAPT
SCHEMBL30494729 0.74 KDM4E (0.51) KDM4ECYP1A2KMT2AMEN1ALPG
SCHEMBL31038760 0.71 KDM4E (0.39) KDM4ECYP1A2KMT2AMEN1ALPG
SCHEMBL11662489 0.68 CYP1A2 (0.39) KDM4ECYP1A2KMT2AMEN1ALPG
SCHEMBL17574484 0.68 MAOB (0.39) KDM4EKMT2AMEN1HTTLMNA
SCHEMBL16684965 0.67 MAOB (0.44) KDM4EKMT2AHTTLMNAMAOB
SCHEMBL31212696 0.67 CYP1A2 (0.44) KDM4ECYP1A2KMT2AMEN1ALPG
SCHEMBL3787340 0.64 HTT (0.49) KDM4ECYP1A2KMT2AMEN1ALPG
SCHEMBL13738007 0.64 JAK1 (0.47) KDM4ECYP1A2KMT2AMEN1ALPG
SCHEMBL11195631 0.64 MAPT (0.57) KDM4EKMT2AMEN1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200254041-A1 RAPID ONSET AND EXTENDED ACTION PLANT-BASED AND SYNTHETIC CANNABINOID FORMULATIONS RECEPTOR HOLDINGS, INC. (US) 2020-08-13 US claimed
EP-3672610-A1 RAPID ONSET AND EXTENDED ACTION PLANT-BASED AND SYNTHETIC CANNABINOID FORMULATIONS Receptor Holdings, Inc. (US) 2020-07-01 EP claimed
EP-3565539-A1 MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS Receptor Holdings, Inc. (US) 2019-11-13 EP claimed
US-20190336472-A1 MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS RECEPTOR HOLDINGS, INC. (US) 2019-11-07 US claimed
WO-2019071213-A1 RAPID ONSET AND EXTENDED ACTION PLANT-BASED AND SYNTHETIC CANNABINOID FORMULATIONS RECEPTOR LIFE SCIENCES, INC. (US) 2019-04-11 WO claimed
WO-2018129097-A1 MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS RECEPTOR LIFE SCIENCES (US) 2018-07-12 WO claimed
US-12636251-B1 Glycoside-containing aqueous formulations having a lipophilic active component Doane Technology Group LLC (US) 2026-05-26 US disclosed
US-20250268861-A1 N-ACYLATED FATTY AMINO ACIDS TO REDUCE ABSORPTION VARIABILITY IN CANNABINOID BASED COMPOSITIONS SPOKE SCIENCES, INC. (US) 2025-08-28 US disclosed
US-12303487-B2 N-acylated fatty amino acids to reduce absorption variability in cannabinoid based compositions SPOKE SCIENCES, INC. (US) 2025-05-20 US disclosed
US-20250152509-A1 PARTICLES, AQUEOUS DISPERSIONS, AND LIQUID COMPOSITIONS HAVING HIGH LIPOPHILIC COMPONENT CONCENTRATIONS AND HIGH LIPOPHILIC COMPONENT TO SURFACTANT RATIOS SPOKE SCIENCES, INC. (US) 2025-05-15 US disclosed
WO-2025090945-A1 FORMULATIONS HAVING A GLYCOSIDE AND A LIPOPHILIC COMPONENT SPOKE SCIENCES, INC. (US) 2025-05-01 WO disclosed
EP-4440556-A2 PARTICLES, AQUEOUS DISPERSIONS, AND LIQUID COMPOSITIONS HAVING HIGH LIPOPHILIC COMPONENT CONCENTRATIONS AND LIPOPHILIC COMPONENT TO SURFACTANT RATIOS Spoke Sciences, Inc. (US) 2024-10-09 EP disclosed
US-20240261303-A1 PARTICLES, AQUEOUS DISPERSIONS, AND COMPOSITIONS HAVING HIGH LIPOPHILIC COMPONENT CONCENTRATIONS AND HIGH LIPOPHILIC COMPONENT TO SURFACTANT RATIOS SPOKE SCIENCES, INC. 2024-08-08 US disclosed
EP-2139333-A4 SUBSTITUTED PYRIDO[3,2-E][1,2,4]TRIAZOLO[4,3-C]PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS MERCK SHARP & DOHME (US) 2010-11-10 EP disclosed
US-20100029697-A1 SUBSTITUTED PYRIDO[3,2-E][1,2,4]TRIAZOLO[4,3-C]PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS MERCK SHARP & DOHME CORP. 2010-02-04 US disclosed
US-20100029697-A1 SUBSTITUTED PYRIDO[3,2-E][1,2,4]TRIAZOLO[4,3-C]PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS MERCK SHARP & DOHME CORP. 2010-02-04 US disclosed
EP-2139333-A1 SUBSTITUTED PYRIDO[3,2-E][1,2,4]TRIAZOLO[4,3-C]PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS Merck & Co., Inc. (US) 2010-01-06 EP disclosed
EP-2139333-A1 SUBSTITUTED PYRIDO[3,2-E][1,2,4]TRIAZOLO[4,3-C]PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS Merck & Co., Inc. (US) 2010-01-06 EP disclosed
WO-2008118414-A1 SUBSTITUTED PYRIDO[3,2-E][1,2,4]TRIAZOLO[4,3-C]PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS MERCK & CO., INC. (US) 2008-10-02 WO disclosed
WO-2008118414-A1 SUBSTITUTED PYRIDO[3,2-E][1,2,4]TRIAZOLO[4,3-C]PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS MERCK & CO., INC. (US) 2008-10-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029697-A1 SUBSTITUTED PYRIDO[3,2-E][1,2,4]TRIAZOLO[4,3-C]PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS CNR1, CNR2, FAAH KDM4E 1920/4885CYP1A2 745/4885KMT2A 3051/4885
US-20250152509-A1 PARTICLES, AQUEOUS DISPERSIONS, AND LIQUID COMPOSITIONS HAVING HIGH LIPOPHILIC COMPONENT CONCENTRATIONS AND HIGH LIPOPHILIC COMPONENT TO SURFACTANT RATIOS NAPEPLD, CNR1, CNR2 KDM4E 4528/4885CYP1A2 1154/4885KMT2A 4471/4885
US-20250268861-A1 N-ACYLATED FATTY AMINO ACIDS TO REDUCE ABSORPTION VARIABILITY IN CANNABINOID BASED COMPOSITIONS FAAH, CNR2, FABP2 KDM4E 1931/4885CYP1A2 593/4885KMT2A 1713/4885
US-20200254041-A1 RAPID ONSET AND EXTENDED ACTION PLANT-BASED AND SYNTHETIC CANNABINOID FORMULATIONS FAAH, CNR1, GPR18 KDM4E 1328/4885CYP1A2 534/4885KMT2A 1353/4885
US-12303487-B2 N-acylated fatty amino acids to reduce absorption variability in cannabinoid based compositions FAAH, CNR2, FABP2 KDM4E 1931/4885CYP1A2 593/4885KMT2A 1713/4885
US-20190336472-A1 MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS GPR18, SLC1A5, CNR2 KDM4E 2063/4885CYP1A2 605/4885KMT2A 1981/4885
US-12636251-B1 Glycoside-containing aqueous formulations having a lipophilic active component CNR2, CNR1, LIPC KDM4E 3730/4885CYP1A2 1304/4885KMT2A 4708/4885
US-20240261303-A1 PARTICLES, AQUEOUS DISPERSIONS, AND COMPOSITIONS HAVING HIGH LIPOPHILIC COMPONENT CONCENTRATIONS AND HIGH LIPOPHILIC COMPONENT TO SURFACTANT RATIOS LIPA, PLIN3, LPL KDM4E 4857/4885CYP1A2 1956/4885KMT2A 4756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.